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AbstractA method for imaging objects in turbid media. According to one embodiment of the invention, the method comprises the steps of (a) illuminating the object through the turbid medium with a pulse of light, the light emergent from the turbid medium consisting of a ballistic component, a snake-like component and a diffusive component, the diffusive component including Fermat photons and non-Fermat photons; (b) gating the light emergent from the turbid medium to preferentially select Fermat photons; and (c) forming an image of the object using the gated light. Preferably, a spatial gate is used to preferentially select Fermat photons from the emergent light. This may be done by orienting the source of the illuminating light and a light detector to lie along a most favorable path travelled predominately by Fermat photons. A time gate, such as a streak camera or the like, may be used in addition to the spatial gate to more carefully select Fermat photons from the emergent light. The above-described method may also be used to produce a tomography map of a turbid medium for use in detecting an object located within the turbid medium. This may be done, for example, by providing two or more pairs of light sources and light detectors which are arranged to provide intersecting most favorable paths. The present invention is also directed to systems constructed in accordance with the foregoing methods.Other References
| InventorsApplicationNo. 384112 filed on 02/03/1995US Classes:356/446With diffusionField of Search356/334, With diffraction grating means356/337, BY PARTICLE LIGHT SCATTERING356/342, Of back-scattered light356/335, FOR SIZE OF PARTICLES356/338, With photocell detection356/336, By particle light scattering356/332, Having adjustable color or bandwidth356/339, At right angles to the light beam (e.g., nephelometer)356/340, At variable angle to the light beam356/333, In a double monochromator356/341, For light comparison means356/343, Using plural photocells356/446, With diffusion250/341.1, With irradiation or heating of object or material250/358.1, With means to inspect passive solid objects250/341.8Measuring infrared radiation reflected from sampleExaminersPrimary: Gonzalez, FrankAssistant: Eisenberg, Jason D. Attorney, Agent or FirmUS Patent References4515165, Apparatus and method for detecting tumorsIssued on: 05/07/1985 Inventor: Carroll5140463, Method and apparatus for improving the signal to noise ratio of an image formed of an object hidden in or behind a semi-opaque random media Issued on: 08/18/1992 Inventor: Yoo, et al.5142372, Three-dimensional optical imaging of semi-transparent and opaque objects using ultrashort light pulses, a streak camera and a coherent fiber bundle Issued on: 08/25/1992 Inventor: Alfano, et al.5203339, Method and apparatus for imaging a physical parameter in turbid media using diffuse waves Issued on: 04/20/1993 Inventor: Knuttel, et al.5227912, Multiple-stage optical Kerr gate system Issued on: 07/13/1993 Inventor: Ho, et al.5275168, Time-gated imaging through dense-scattering materials using stimulated Raman amplification Issued on: 01/04/1994 Inventor: Reintjes, et al.5299035, Holographic imaging through scattering media Issued on: 03/29/1994 Inventor: Leith, et al.5349951, Optical CT imaging device Issued on: 09/27/1994 Inventor: Ito, et al.5353799, Examination of subjects using photon migration with high directionality techniques Issued on: 10/11/1994 Inventor: Chance5369496, Noninvasive method and apparatus for characterizing biological materials Issued on: 11/29/1994 Inventor: Alfano, et al.5371368, Ultrafast optical imaging of objects in a scattering medium Issued on: 12/06/1994 Inventor: Alfano, et al.5416582, Method and apparatus for localization and spectroscopy of objects using optical frequency modulation of diffusion waves Issued on: 05/16/1995 Inventor: Knutson, et al.5418797Time gated imaging through scattering material using polarization and stimulated raman amplification Issued on: 05/23/1995 Inventor: Bashkansky, et al. International ClassesA61B 005/00A61B 006/00 |