Synthetic peptide lung surfactants having covalently bonded antioxidants
Patent 5623052 Issued on April 22, 1997. Estimated Expiration Date: 
July 14, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
July 14, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesSynthetic pulmonary surfactant Patent #: 4861756 InventorsAssigneeApplicationNo. 502722 filed on 07/14/1995US Classes:530/330, 4 to 5 amino acid residues in defined sequence530/331Tripeptides, e.g., tripeptide thyroliberin (TRH), melanostatin (MIF), etc.ExaminersPrimary: Davenport, Avis M.Attorney, Agent or FirmForeign Patent References
International ClassesA61K 038/00C07K 005/00 C07K 007/00 AbstractSynthetic pulmonary surfactants having antioxidant properties consisting of a complex of a polypeptide of 3-4 amino acid residues, with an antioxidant moiety, and a lipid consisting of one or more of the lipids associated with natural pulmonary surfactant were prepared. These surfactants are useful in the treatment of respiratory distress syndrome.Other References
Field of Search4 to 5 amino acid residues in defined sequenceTripeptides, e.g., tripeptide thyroliberin (TRH), melanostatin (MIF), etc. Chemical modification or the reaction product thereof, e.g., covalent attachment or coupling, etc. 5 or 6 peptide repeating units in known peptide chain 3 or 4 peptide repeating units in known peptide chain |
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