Sugar base surfactant for nanocrystals
Patent 5622938 Issued on April 22, 1997. Estimated Expiration Date: 
May 19, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 19, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesInjectable compositions, nanoparticles useful therein, and process of manufacturing same Process for the preparation of activated pharmaceutical compositions 5118528 Surface modified drug nanoparticles Amphiphilic compounds containing two sugar or sugar-derived head groups Patent #: 5403922 InventorApplicationNo. 444796 filed on 05/19/1995US Classes:514/35, Oxygen of the saccharide radical bonded directly to a cyclohexyl ring424/1.29, Coated, impregnated, or colloidal particulate (e.g., microcapsule, micro-sphere, micro-aggregate, macro-aggregate)424/9.45, Halogenated benzene ring containing424/490, Coated (e.g., microcapsules)424/493, Containing polysaccharides (e.g., sugars)424/499, Contains proteins or derivative or polysaccharides or derivative510/470CarbohydrateExaminersPrimary: Nutter, Nathan M.Attorney, Agent or FirmInternational ClassesA01N 043/04A61K 031/70 AbstractDispersible particles consisting essentially of a crystalline drug substance having a surface modifier having the formula: ##STR1## wherein R is phenyl-(CH2)10 CO or C12 H25 NHCO adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 400 nm, methods for the preparation of such particles and dispersions containing the particles. Pharmaceutical compositions containing the particles exhibit unexpected bioavailability and are useful in methods of treating mammals.Other References
Field of SearchOxygen of the saccharide radical bonded directly to a cyclohexyl ringCoated (e.g., microcapsules) Containing polysaccharides (e.g., sugars) Contains proteins or derivative or polysaccharides or derivative Coated, impregnated, or colloidal particulate (e.g., microcapsule, micro-sphere, micro-aggregate, macro-aggregate) | |
