U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method for the treatment of periodontal disease by sustained delivery of a therapeutic agent to the periodontal pocket, composition of matter therefor and apparatus for the administration thereof

Patent 5622498 Issued on April 22, 1997. Estimated Expiration Date: Icon_subject April 22, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3760503

Metal coated articles
Patent #: 3939834
Issued on: 02/24/1976
Inventor: McMahon

Cannula and process
Patent #: 4276880
Issued on: 07/07/1981
Inventor: Malmin

Process for preparation of microcapsules
Patent #: 4622244
Issued on: 11/11/1986
Inventor: Lapka ,   et al.

Local delivery of chemotherapeutic agents for the treatment of periodontal disease
Patent #: 4685883
Issued on: 08/11/1987
Inventor: Jernberg

Intra-pocket drug delivery devices for treatment of periodontal diseases
Patent #: 4764377
Issued on: 08/16/1988
Inventor: Goodson

Applicator syringe for a dental compound
Patent #: 4798596
Issued on: 01/17/1989
Inventor: Muhlbauer

Single hand operable dental composite package
Patent #: 4863072
Issued on: 09/05/1989
Inventor: Perler

Apparatus for the treatment of periodontal disease Patent #: 5236355
Issued on: 08/17/1993
Inventor: Brizzolara, et al.

Inventors

Assignee

Application

No. 007753 filed on 01/22/1993

US Classes:

433/80, Having intra-oral dispensing means433/89, Hand-held implement with material supply604/187Injector or aspirator syringe supported only by person during use (e.g., hand held hypodermic syringe, douche tube with forced injection, etc.)

Examiners

Primary: O'Connor, Cary E.

Attorney, Agent or Firm

International Classes

A61C 017/02
A61C 005/04
A61M 005/00

Abstract

Oral compositions for the local administration of a therapeutic agent to a periodontal pocket of a patient for alleviating dental disease comprise a plurality of dry, discrete microparticles each of which comprise an effective amount of at least one therapeutic agent dispersed in a matrix comprising a biocompatible and biodegradable polymer. Apparatus and methods are also provided for the dispensing of the dry microparticles to the periodontal pocket whereby they become tacky and adhere to the involved tissue so as to induce long term therapeutic benefits.

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