U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Injectable drug delivery system and method

Patent 5620700 Issued on April 15, 1997. Estimated Expiration Date: Icon_subject May 9, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Dynamic implants and method for implanting the same
Patent #: 3982537
Issued on: 09/28/1976
Inventor: Bucalo

4030499

Implants for acting on living beings
Patent #: 4054138
Issued on: 10/18/1977
Inventor: Bucalo

Polymeric orthoesters housing beneficial drug for controlled release therefrom
Patent #: 4066747
Issued on: 01/03/1978
Inventor: Capozza

Poly(orthoester) co- and homopolymers and poly(orthocarbonate) co- and homopolymers having carbonyloxy functionality
Patent #: 4070347
Issued on: 01/24/1978
Inventor: Schmitt

Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates)
Patent #: 4093709
Issued on: 06/06/1978
Inventor: Choi, et al.

Polymeric orthoesters
Patent #: 4119579
Issued on: 10/10/1978
Inventor: Capozza

Structured orthoester and orthocarbonate drug delivery devices
Patent #: 4131648
Issued on: 12/26/1978
Inventor: Choi ,   et al.

Polymeric orthoesters having arylene arrangement
Patent #: 4136252
Issued on: 01/23/1979
Inventor: Capozza

Erodible agent releasing device comprising poly(orthoesters) and poly(orthocarbonates)
Patent #: 4138344
Issued on: 02/06/1979
Inventor: Choi ,   et al.

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Inventors

Assignee

Application

No. 437471 filed on 05/09/1995

US Classes:

424/435, Mouth424/422, Implant or insert424/426, Errodable, resorbable, or dissolving523/105, Nonmedicated composition specifically intended for contact with living animal tissue or process of preparing; other than apparel523/113Composition suitable for use as tissue or body member replacement, restorative, or implant

Examiners

Primary: Hulina, Amy

Attorney, Agent or Firm

Foreign Patent References

  • 0290983 EP 05/13/1988
  • 0100981 EP 01/13/1989
  • 0352588 EP 07/13/1989

International Class

A61K 006/00

Abstract

The present invention is directed to a material which can be used to deliver a drug, such as an antibiotic, into a diseased tissue pocket, such as a periodontal pocket. The material is preferably a bioerodible oligomer or polymer. The oligomer or polymer containing the drug is heated and is then delivered, preferably by injection, into the tissue pocket at a physiologically compatible elevated temperature. Once the bioerodible material is injected into the pocket, the material cools to the body temperature of the pocket. As it cools, the material hardens and remains in place in the tissue pocket. The hardened material bioerodes in the pocket and releases the drug over a period of several days.

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