Patent ReferencesDynamic implants and method for implanting the same 4030499 Implants for acting on living beings Polymeric orthoesters housing beneficial drug for controlled release therefrom Poly(orthoester) co- and homopolymers and poly(orthocarbonate) co- and homopolymers having carbonyloxy functionality Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates) Polymeric orthoesters Structured orthoester and orthocarbonate drug delivery devices Polymeric orthoesters having arylene arrangement Erodible agent releasing device comprising poly(orthoesters) and poly(orthocarbonates) Inventors
AssigneeApplicationNo. 437471 filed on 05/09/1995US Classes:424/435, Mouth424/422, Implant or insert424/426, Errodable, resorbable, or dissolving523/105, Nonmedicated composition specifically intended for contact with living animal tissue or process of preparing; other than apparel523/113Composition suitable for use as tissue or body member replacement, restorative, or implantExaminersPrimary: Hulina, AmyAttorney, Agent or FirmForeign Patent References
International ClassA61K 006/00AbstractThe present invention is directed to a material which can be used to deliver a drug, such as an antibiotic, into a diseased tissue pocket, such as a periodontal pocket. The material is preferably a bioerodible oligomer or polymer. The oligomer or polymer containing the drug is heated and is then delivered, preferably by injection, into the tissue pocket at a physiologically compatible elevated temperature. Once the bioerodible material is injected into the pocket, the material cools to the body temperature of the pocket. As it cools, the material hardens and remains in place in the tissue pocket. The hardened material bioerodes in the pocket and releases the drug over a period of several days. | |