Patent References 3888864 3917582 Aminophenyl esters of 5-carboxyalkyl barbituric acids Immunoassay for phencyclidine Specific binding assay method and reagent means Amitriptyline conjugates to antigenic proteins and enzymes Theophylline antigens and antibodies Imipramine derivatives and poly(amino acid) conjugates Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers Diagnostic test for barbiturates InventorsAssigneeApplicationNo. 249676 filed on 05/26/1994US Classes:530/403, Protein is identified as an antigen, e.g., immunogenic carriers, etc.436/533, Carrier is water suspendible particles (e.g., latex, etc.)436/815, TEST FOR NAMED COMPOUND OR CLASS OF COMPOUNDS436/816, Alkaloids, amphetamines, and barbiturates530/404, Sulfur containing reactant530/405, Nitrogen containing reactant530/807, HAPTEN CONJUGATED WITH PEPTIDE OR PROTEIN530/816Attached to the carrier via a bridging agentExaminersPrimary: Ceperley, Mary E.Attorney, Agent or FirmForeign Patent References
International ClassesC07K 017/06G01N 033/547 AbstractNovel reagents for the detection by immunoassay of drugs in body fluids, their preparation and use are disclosed. The reagents of the present invention correspond to the formulaP--[A--D]nwhere:D is a drug derivative suitably selective for the determination of the presence of the target drug or drug metabolite,A is an activating linker-spacer group having an N-hydroxysuccinimide or isothiocyanate derived linking moiety,P is a poly(amino acid) or polymer capable of covalently bonding with A, andn is less than l.Other References
Field of SearchProtein is identified as an antigen, e.g., immunogenic carriers, etc.Sulfur containing reactant Nitrogen containing reactant Serum albumin, e.g., BSA, HSA, etc. Ovalalbumin, e.g., avidin, conalbumins, etc. Blood proteins or globulins, e.g., proteoglycans, platelet factor 4, thyroglobulin, thyroxine, etc. HAPTEN CONJUGATED WITH PEPTIDE OR PROTEIN Attached to the carrier via a bridging agent Carrier is water suspendible particles (e.g., latex, etc.) TEST FOR NAMED COMPOUND OR CLASS OF COMPOUNDS PEPTIDE, PROTEIN OR AMINO ACID |
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