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Tetrahydro-1H-benzazepinones and hexahydroazepinones as selective cholecystokinin-B receptor antagonists

Patent 5618811 Issued on April 8, 1997. Estimated Expiration Date: Icon_subject January 18, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventor

Application

No. 586685 filed on 01/18/1996

US Classes:

514/218, Hetero ring is seven-membered consisting of two nitrogens and five carbon atoms514/221, Bicyclo ring system having the seven-membered hetero ring as one of the cyclos540/523, Bicyclo ring system which contains the hetero ring as one of the cyclos540/524, Additional hetero ring containing540/527Nitrogen bonded directly to the hetero ring

Examiners

Primary: Bond, Robert T.

Attorney, Agent or Firm

Foreign Patent References

  • 487207 EP 05/13/1992
  • WO/15059 WO 08/13/1993

International Classes

A61K 031/55
C07D 223/12

Abstract

This invention relates to compounds of formula (I) wherein R1, R2, R3, R4 and X are as defined in the application. These compounds are CCK-B receptor antagonists and are useful in the treatment and prevention of central nervous system and gastrointestinal disorders. ##STR1##

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