U.S. patents available from 1976 to present.
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Nitrosylated neuropeptides

Patent 5612314 Issued on March 18, 1997. Estimated Expiration Date: Icon_subject April 21, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

S-nitrosothiols as smooth muscle relaxants and therapeutic uses thereof
Patent #: 5380758
Issued on: 01/10/1995
Inventor: Stamler, et al.

Treatments for male sexual dysfunction
Patent #: 5439938
Issued on: 08/08/1995
Inventor: Snyder, et al.

Method and agents for control and management of labor during pregnancy Patent #: 5508045
Issued on: 04/16/1996
Inventor: Harrison, et al.

Inventors

Assignee

Application

No. 426935 filed on 04/21/1995

US Classes:

514/13, 16 to 24 peptide repeating units in known peptide chain524/14, At least one solid polymer or SICP derived from at least one nonethylenic reactant524/15, Vegetable shell, hull, or cob ingredient, e.g., nut shells, pits, etc.524/16, Bark or cork524/17, Protein or biologically active polypeptide DNRM excluding wheat flour or natural cereals which may contain protein ingredient530/324, 25 or more amino acid residues in defined sequence530/325, 24 amino acid residues in defined sequence530/326, 15 to 23 amino acid residues in defined sequence530/327, 11 to 14 amino acid residues in defined sequence530/328, 8 to 10 amino acid residues in defined sequence530/3296 to 7 amino acid residues in defined sequence

Examiners

Primary: Cain, Edward J.

Attorney, Agent or Firm

International Class

A61K 037/00

Abstract

Neuropeptides, particularly vasoactive intestinal peptide(VIP) and fragments, mutations and derivatives thereof that have corresponding activities to which have been directly or indirectly linked at least one NO or NO2 group, and their uses, including the relaxation of smooth muscle in several tissues, including vascular smooth muscle (e.g., aorta) and nonvascular smooth muscle (e.g. trachea, sphincter of Oddi, gastrointestinal smooth muscle and corpus cavernosum smooth muscle), and particularly also for the diagnosis and treatment of human male impotence.

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