Radiation treatment of tumors using inflatable devices
Patent 5611767 Issued on March 18, 1997. Estimated Expiration Date: September 16, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Methods and apparatus are provided for radiation treatment of a tumor using an inflatable treatment device placed in an incision adjacent the tumor. The inflatable device is filled with a radioactive treatment fluid.
Exhibit A-- catalog page of American Heyer-Schulte (undated but admitted to be prior art)
J. Neurosurg., vol. 39, Sep., 11973, pp. 315-322, Garfield et al., "Postoperative intracavitary chemotherapy of malignant gliomas"
NASA Tech Briefs, Jun., 1990, at p. 106
Int. J. Radiation Oncology Bio. Phys., Nov., 1988, vol. 15, pp. 1203-1208, Shimm et al., "Scanned Focussed Ultrasound Hyperthermia: Initial Crucial Results"
J. Neorosurg., vol. 64, Apr., 1986, Roberts et al., "Interstitial hyperthermia and iridium brachytherapy in treatment of malignant gliomas"
The British Journal of Radiology, Feb., 1989, Chun et al., "Interstitial iridium-192 implantation for malignant brain tumours Part II", pp. 158-162
Am. J. Clin. Oncol. (CCT), vol. 10, No. 2, 1987, at p. 106, item (13)
J. Neurosurg., vol. 60, Jan., 1984, Gutin et al., "Brachytherapy of recurrent malignant brain tumors with removable high-activity iodine-125 sources"
The British Journal of Radiology, Feb., 1989, Wu et al., "Interstitial iridium-192 implantation for malignant brain tumours Part I", pp. 154-157
J. Radiation Oncology Biol. Phys., vol. 17, pp. 615-622, Raaphorst, et al., "A Comparison of Heat and Radiation Sensitivity of Three Human Glioma Cell Lines"
Exhibit B-- Brochure of Halkey-Roberts Corporation of St. Petersburg, Florida (Undated but admitted to be prior art)
J. Biomed. Mater. Res., vol. 10, pp. 327-334 (1976), Moidel et al., "Materials for Selective Tissue Heating in a Radiofrequency Electromagnetic Field for the Combined Chemothermal Treatment of Brain Tumors