U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

L-DOPA ethyl ester to treat Parkinson's disease

Patent 5607969 Issued on March 4, 1997. Estimated Expiration Date: Icon_subject May 17, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3803120

Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease
Patent #: 3939253
Issued on: 02/17/1976
Inventor: Bodor ,   et al.

Effervescent enteric coated L-dopa formulation and method of using the same
Patent #: 3961041
Issued on: 06/01/1976
Inventor: Nishimura ,   et al.

Novel, transient pro-drug forms of L-DOPA to treat Parkinson's disease
Patent #: 4035507
Issued on: 07/12/1977
Inventor: Bodor ,   et al.

Rectally absorbable form of L-dopa
Patent #: 4663349
Issued on: 05/05/1987
Inventor: Repta

Pharmaceutical compositions containing levodopa methyl ester, preparation and therapeutic applications thereof
Patent #: 4826875
Issued on: 05/02/1989
Inventor: Chiesi

Method of treating parkinson's syndrome Patent #: 4916151
Issued on: 04/10/1990
Inventor: Bey, et al.

Inventors

Assignee

Application

No. 442888 filed on 05/17/1995

US Classes:

514/538Nitrogen bonded to carbon in Z moiety

Examiners

Primary: Criares, Theodore J.

Attorney, Agent or Firm

Foreign Patent References

  • 1364505 GB. 09/13/1974

International Class

A61K 031/24

Abstract

Patients suffering from Parkinson's disease are treated by administering a composition which contains an active ingredient and a pharmaceutically acceptable carrier. The active ingredient comprises L-DOPA ethyl ester in an amount which is at least 97% by weight of the active ingredient and L-DOPA in an amount which is less than 1% by weight of the active ingredient.

Other References

  • D.R. Cooper et al., "L-Dopa esters as potential prodrugs; behavioural actty in experimental models of Parkinson's disease"; J. Pharm. Pharmacol.; vol. 39: No.8; pp. 627-635
  • Cooper, D.R., et al., Clin. Neuropharmacol. (1984) 7:89-98
  • Fix, J.A., et al., Pharm. Res. (1989) 6:501-505
  • Juncos, J.L., et al., Neurology (1987) 37:1242-1245
  • Lai, C.M., et al., J. Pharm. Sci. (1973) 62:510-511
  • Yoshimasa Tomiuchi, et al. Bull. Chem. Soc. Jpn. (Oct. 1992) 65:2599-260
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$16.95more info
 
Sign InRegister
Username  
Password   
forgot password?