Iron lactoferrin complexes and preparation thereof
Patent 5606086 Issued on February 25, 1997. Estimated Expiration Date: 
April 24, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 24, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesProcess for the selective extraction of metalloproteins from whey by adsorption and elution 5116953 Method for isolating and purifying transferrin and lactoferrin receptor proteins and vaccines containing the same Patent #: 5141743 InventorsApplicationNo. 318778 filed on 04/24/1995US Classes:556/138, Iron, cobalt, or nickel containing (Fe, Co, or Ni)530/394, Beta globulins, e.g., transferrin, etc.530/395, Glycoprotein, e.g., mucins proteoglycans, etc.530/400, Metal containing, e.g., chromoproteins, ferritin, ferredoxins, etc.556/147, The chalcogen is part of a -C(=X)X- group, wherein the X's are the same or diverse chalcogens556/148Nitrogen containing (e.g., ferric chelates of ethylenediaminetetracetic acid, etc.)ExaminersPrimary: Nazario-Gonzalez, PorfirioAttorney, Agent or FirmInternational ClassC07F 015/02Foreign Application Priority Data1993-12-16 JPAbstractHeat resistant carbonate- and/or hydrogencarbonate-iron-Lf complexes in which one molecule of lactoferrin is bound with 15 molecules or over of iron via carbonic acid and/or hydrogencarbonic acid.Process for the production of above mentioned complexes prepared by adjusting pHࣘ7 by adding alkali salts of carbonic acid and/or hydrogencarbonic acid to an aqueous solution containing an iron salt exhibiting pHࣘ4 when dissolved in water and lactoferrins, or adding an iron salt and lactoferrin solution to carbonic acid and/or hydrogencarbonic acid solution, or adding the iron salt or its solution to a solution containing carbonic acid and/or hydrogencarbonic acid and lactoferrins.The resultant lactoferrin complexes are highly heat resistant and useful as raw materials of foods, medicines, feeds, cosmetics and so forth.Field of SearchIron, cobalt, or nickel containing (Fe, Co, or Ni)The chalcogen is part of a -C(=X)X- group, wherein the X's are the same or diverse chalcogens Nitrogen containing (e.g., ferric chelates of ethylenediaminetetracetic acid, etc.) Metal containing, e.g., chromoproteins, ferritin, ferredoxins, etc. Beta globulins, e.g., transferrin, etc. Glycoprotein, e.g., mucins proteoglycans, etc. |
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