U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

3-(2-trialkylsilyloxy)ethyl-7-ethyl-1H-indoles and method for their preparation

Patent 5599946 Issued on February 4, 1997. Estimated Expiration Date: Icon_subject May 30, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Certain pyrano [3,4-b]indoles and thiopyrano[3,4-b]indoles
Patent #: 3939178
Issued on: 02/17/1976
Inventor: Demerson ,   et al.

Process for preparing 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)-indole-1-acetic acid, etodolac Patent #: 4585877
Issued on: 04/29/1986
Inventor: Demerson ,   et al.

Inventors

Application

No. 453740 filed on 05/30/1995

US Classes:

548/432Pyrano(3,4-b)indoles or thiopyrano(3,4-b) indoles (including hydrogenated)

Examiners

Primary: Morris, Patricia L.

Attorney, Agent or Firm

International Class

C07D 491/052

Abstract

The present invention relates to novel trialkylsilyloxy derivatives of 7-ethyltryptophol useful in the preparation of etodolac, and methods of making them, and methods of using them to prepare etodolac.

Other References

  • P. Rib ereau-Gayon et al., "Rural Economy.--Simultaneous analysis of organic acids, polyalchohols, and sugars in wine. Applications.", C. R. Acad. Sc. Paris, t. 273, Sries D-1761, 8 Nov. 1971, 2 pages (together with English translation
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