Tocotrienols and tocotrienol-like compounds and methods for their use
August 15, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3064012 3122565 Free-flowing, high density, fat soluble vitamin powders with improved stability Phospholipase A2 inhibitors Compositions and method for stabilization of anthralin comprising the addition of an oil soluble antioxidant and an anionic surfactant Extractive separation method Farnesylated tetrahydro-naphthalenols as hypolipidemic agents Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders Farnesylated tetrahydro-naphthalenols as hypolipidemic agents Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders InventorsAssigneeApplicationNo. 244215 filed on 08/15/1994US Classes:514/458, Tocopherols (e.g., vitamin E, etc.)549/401, Chalcogen bonded directly to the ring carbon para to the ring oxygen (e.g., chromones, etc.)549/408Chalcogen bonded directly to the carbocyclic ring of the bicyclo ring system (e.g., tocopherols, etc.)ExaminersPrimary: Raymond, Richard L.Attorney, Agent or FirmForeign Patent References
International ClassesA61K 031/355C07D 311/22 C07D 311/72 AbstractThe present invention relates to novel tocotrienols and tocotrienol-like compounds displaying biological activity. The tocotrienols and tocotrienol-like compounds of this invention may be conveniently obtained from biological sources or by chemical synthesis and may be used in pharmaceutical compositions, foodstuffs and dietary supplements. This invention also relates to the use of tocotrienols, tocotrienol-like compounds, and mixtures thereof, as hypocholesterolemic, antithrombotic, antioxidizing, antiatherogenic, antiinflammatory and immunoregulatory agents, or as agents useful to decrease lipoprotein (a) concentration in the blood or to increase feed conversion efficiency.Other References
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