Membrane holder
Patent 5591636 Issued on January 7, 1997. Estimated Expiration Date: 
July 24, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
July 24, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3186917 3386912 3508656 3520803 3590634 Blood purification means Mammalion cell culture process Device for detecting and measuring the concentration of gaseous hydrogen dissolved in a fluid Perfusion chamber Method of tissue growth InventorAssigneeApplicationNo. 505921 filed on 07/24/1995US Classes:435/287.1, Including measuring or testing73/38, Porosity or permeability73/64.47, Osmotic pressure (e.g., diffusion characteristic)324/71.1, DETERMINING NONELECTRIC PROPERTIES BY MEASURING ELECTRIC PROPERTIES324/450, Which includes particular cell container structure422/101, Including means for separating a constituent; e.g., filter, condenser, extractor, etc.435/287.9, Including a coated reagent or sample layer435/297.2Including perfusion meansExaminersPrimary: Beisner, William H.Attorney, Agent or FirmInternational ClassesC12M 001/12C12M 001/34 305.2 288.4 303.1 288.5 809 817 AbstractThe invention provides a compact device of simple construction for holding a membrane in contact with a pair of fluids, one on each side of the membrane. According to the invention, the membrane holder comprises a base and an upper cap, with the membrane held between them. Fluids may be circulated over the surfaces of the membrane. Electrode ports are provided through which electrodes may be placed in proximity to the membrane for measuring or applying electrical potential across the membrane. The membrane holder comprises a base, which includes a lower plate and a center plate secured thereto, and an upper cap, which screws into the base by means of a threaded connection between them. The upper cap may be sealed to provide an enclosed volume for holding one of the fluids or the upper cap may be open to provide an open reservoir for holding the fluid. One or more membrane holders according to the invention may be placed in and held by a specially constructed heater stand. The heater stand includes internal channels for circulating a temperature controlled fluid through the heater stand to transfer heat to or from the base of the membrane holder.Other References
Field of SearchInvolving viable micro-organismTREATMENT OF MICRO-ORGANISMS OR ENZYMES WITH ELECTRICAL OR WAVE ENERGY (E.G., MAGNETISM, SONIC WAVES, ETC.) Cell membrane or cell surface is target Membrane permeability increased Electroporation Including measuring or testing Including a coated reagent or sample layer Including multiple internal compartments or baffles Including perfusion means In combination with a dish, plate, or tray Including semipermeable membrane or filter Including multiple internal compartments for baffles Miscellaneous laboratory apparatus and elements, per se Including means for separating a constituent; e.g., filter, condenser, extractor, etc. Container Holder, support, housing, or hood Porosity or permeability Osmotic pressure (e.g., diffusion characteristic) Planar membrane Planar membrane With membrane Selectively permeable membrane Analysis and testing Using a conductivity determining device Which includes current and voltage electrodes Having conductance probe structure Which includes particular cell container structure With living organism condition determination using conductivity effects DETERMINING NONELECTRIC PROPERTIES BY MEASURING ELECTRIC PROPERTIES |
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