Milled naproxen with hydroxypropyl cellulose as a dispersion stabilizer
Patent 5591456 Issued on January 7, 1997. Estimated Expiration Date: 
February 10, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 10, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesMethod for making uniformly sized particles from water-insoluble organic compounds Surface modified drug nanoparticles Patent #: 5145684 InventorsApplicationNo. 386790 filed on 02/10/1995US Classes:424/494, Cellulose derivatives424/493, Containing polysaccharides (e.g., sugars)424/499, Contains proteins or derivative or polysaccharides or derivative514/781, Cellulose or derivative514/951POWDERS, GRANULES OR PARTICLES OF SPECIFIED MESH OR PARTICLE SIZEExaminersPrimary: Spear, James M.Attorney, Agent or FirmInternational ClassesA61K 009/18A61K 009/14 AbstractDispersible particles consisting essentially of crystalline NSAID having hydroxypropyl cellulose adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm. Pharmaceutical compositions containing the particles exhibit unexpectedly reduced gastric irritation following oral administration and/or hastened onset of action.Other References
Field of SearchParticulate form (e.g., powders, granules, beads, microcapsules, and pellets)Cellulose derivatives Containing polysaccharides (e.g., sugars) Contains proteins or derivative or polysaccharides or derivative Cellulose or derivative POWDERS, GRANULES OR PARTICLES OF SPECIFIED MESH OR PARTICLE SIZE | |
