U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Crystalline form of a cephalosporin antibiotic

Patent 5589593 Issued on December 31, 1996. Estimated Expiration Date: Icon_subject June 7, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3925372

Method for preparing crystalline cefadroxil monohydrate
Patent #: 4898938
Issued on: 02/06/1990
Inventor: Marsili

Process for preparing well crystallized alkali metal salts of 3, 7-substituted 7-aminocephalosporanic acid derivatives
Patent #: 5142042
Issued on: 08/25/1992
Inventor: Chang, et al.

Crystalline cephem acid addition salts and process for their preparation Patent #: 5409918
Issued on: 04/25/1995
Inventor: Adam, et al.

Inventors

Application

No. 483888 filed on 06/07/1995

US Classes:

540/220, Purification or recovery540/2151-thia-5-aza-bicyclo(4.2.0)octane (including unsaturated; e.g., cepham, etc.)

Examiners

Primary: Ford, John M.
Assistant: Sripada, Pavanaram K.

Attorney, Agent or Firm

Foreign Patent References

  • 0429895A1 EP. 06/13/1991

International Class

C07D 501/32

Foreign Application Priority Data

1991-11-11 IT

Abstract

The preparation of a novel crystalline cefaclor and the conversion of such a product to cefaclor monohydrate are described. The new intermediate cefaclor is a particular crystalline form and possesses the same antibiotic properties as cefaclor monohydrate.

Other References

  • Journal of Medicinal Chemistry vol. 18, No. 14, Apr. 1975 Washington pp. 403-408
  • Lorenz, Analytical Profile of Drug Substances, pp. 108-123 (1980) Academic Pres
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