U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Medical uses of in situ formed gels

Patent 5587175 Issued on December 24, 1996. Estimated Expiration Date: Icon_subject December 28, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3590125

3640741

3867521

Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
Patent #: 4100271
Issued on: 07/11/1978
Inventor: Krezanoski

Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
Patent #: 4188373
Issued on: 02/12/1980
Inventor: Krezanoski

Osmotic drug delivery system
Patent #: 4439196
Issued on: 03/27/1984
Inventor: Higuchi

Ophthalmic drug delivery system utilizing thermosetting gels
Patent #: 4474751
Issued on: 10/02/1984
Inventor: Haslam ,   et al.

Drug delivery system utilizing thermosetting gels
Patent #: 4474752
Issued on: 10/02/1984
Inventor: Haslam ,   et al.

Safety door lock
Patent #: 4475753
Issued on: 10/09/1984
Inventor: D'Ath

Drug delivery system utilizing thermosetting gels
Patent #: 4478822
Issued on: 10/23/1984
Inventor: Haslam ,   et al.

More ...

Inventors

Assignee

Application

No. 174101 filed on 12/28/1993

US Classes:

424/427, Ocular424/78.02, TOPICAL BODY PREPARATION CONTAINING SOLID SYNTHETIC ORGANIC POLYMER AS DESIGNATED ORGANIC ACTIVE INGREDIENT (DOAI)424/78.17, Aftertreated polymer (e.g., grafting, blocking, etc.)424/78.18, Polymer derived from ethylenic monomers only424/78.26, Chemical treating agent contains element other than C, H, O, alkali, or alkaline earth metal424/78.37, Monomer contains oxygen424/430, Vaginal, urethral, uterine424/436, Anal, rectal (e.g., suppositories, etc.)424/486, Synthetic polymer424/488, Polysaccharides (e.g., cellulose, etc.)424/497, Containing solid synthetic polymers514/772.7, Heterocyclic monomer514/779, Algin or derivative514/912, OPHTHALMIC514/913, Glaucoma514/914, Inflammation514/944, GEL514/966, RECTAL514/967, VAGINAL523/122, Composition having ingredient providing biocidal or biostatic protection thereto or process of preparing623/5.11, Corneal implant623/905Eye

Examiners

Primary: Azpuru, Carlos

Attorney, Agent or Firm

Foreign Patent References

  • 0386960 EP. 02/13/1990
  • 0517160 EP. 02/13/1992

International Classes

A61K 031/77
A61K 031/725
A61K 031/73
A61K 002/14

Abstract

Balanced pH, hyperosmotic, hypoosmotic, or isoosmotic gels are ideal vehicles for drug delivery. They are especially suited for topical body cavity or injection application of drugs or diagnostic agents; for drug or diagnostic agent delivery to the eye of a mammal; as protective corneal shields; or as ablatable corneal masks useful in laser reprofiling of the cornea. The compositions without the addition of a drug or diagnostic agent are useful as medical devices, for instance, in separating surgically or otherwise injured tissue as a means of preventing adhesions.

Other References

  • Kim, et al., "Pluronic.RTM. Polyol: A Potential Alloplastic Keratorefractive Material"; Journal of Cataract Refractive Surgery, vol. 14, May 1988, pp. 312-316
  • Bodmeier et al. (1989), J. Pharmaceutical Sciences, vol. 78(11), pp. 964-967
  • Amies, C. R. (1959), J. Pathology & Bacteriology, vol. 77, pp. 435-442
  • Pfister et al. (1986), J. Controlled Release, vol. 3, pp. 229-233
  • Poland et al. (1988), J. Cataract Refractive Surgery, vol. 14, pp. 489-491
  • Trokel et al. (1983), Am. J. Ophthalmol., vol. 96, pp. 710-715
  • Marshall et al. (1985), Ophthalmology, vol. 92, pp. 749-758
  • Cotliar et al. (1985), Ophthalmology, vol. 92, pp. 206-208
  • Puliafito, C. A. (1985), Ophthalmology, vol. 92, pp. 741-748
  • Kruegar and Trokel (1985), Arch. Opthalmol., vol. 103, pp. 1741-1742
  • Hanna et al. (1989), Arch. Ophthalmol., vol. 107, pp. 895-901
  • Taylor et al. (1989), Ophthalmology, vol. 96, pp. 654-664
  • Hanna et al. (1988), Arch. of Ophthalmology, vol. 106, pp. 245-250
  • Search Results Dialog, Dec. 23, 1993
  • Search Results Dialog, Dec. 29, 1993
  • Shofner et al. (1989), Ophthalmology Clinics of North America, vol. 2(1), pp. 15-23
  • Fantes et al. (1990), Arch. Ophthalmol., vol. 108, pp. 665-67
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$16.95more info
 
Sign InRegister
Username  
Password   
forgot password?