U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Site-specific adhesion within the GI tract using nanoparticles stabilized by high molecular weight, linear poly (ethylene oxide) polymers

Patent 5580579 Issued on December 3, 1996. Estimated Expiration Date: Icon_subject February 15, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Surface modified drug nanoparticles Patent #: 5145684
Issued on: 09/08/1992
Inventor: Liversidge, et al.

Inventors

Application

No. 388878 filed on 02/15/1995

US Classes:

424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/498, Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof514/937, DISPERSION OR EMULSION514/938, Oil-water type514/939, Mineral oil-water type514/943Higher fatty acid or derivative containing

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

International Classes

A61K 009/107
A61K 123/00

Abstract

Nanoparticulate crystalline therapeutic or diagnostic substances formulated with stabilizers and high molecular weight, linear poly(ethylene oxide) polymers, enhance contact between the crystalline therapeutic or diagnostic substances and the gastrointestinal tract providing site-specific and extended therapeutic or diagnostic effect.

Other References

  • Kinam Park and Joseph R. Robinson, "Bioadhesive polymers as platforms for oral-controlled drug delivery: method to study bioadhesion", 1984, pp. 107-12
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