Method for inhibiting tumor growth rate using creatine or creatine analogs
Patent 5576316 Issued on November 19, 1996. Estimated Expiration Date: 
April 4, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 4, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesTreatment of human tumors utilizing compounds having a phosphoamides linkage or enol phosphate linkage Method of inhibiting transformation of cells in which purine metabolic enzyme activity is elevated Patent #: 5324731 InventorAssigneeApplicationNo. 416499 filed on 04/04/1995US Classes:514/218, Hetero ring is seven-membered consisting of two nitrogens and five carbon atoms514/275, Nitrogen bonded directly to the 1,3-diazine at 2-position by a single bond514/385, 1,3-diazoles514/386, Divalent chalcogen or acyclic nitrogen double bonded directly to ring carbon of the diazole ring, or tautomeric equivalent514/396, Imidazoles514/553, Radical -XH acid, or anhydride, acid halide or salt thereof (X is chalcogen) DOAI514/561, Nitrogen other than as nitro or nitroso nonionically bonded514/563, RC(=O)N containing (i.e., carboxamide) (R is C or H)514/564, Plural nitrogens nonionically bonded514/579, Nitrogen containing other than solely as a nitrogen in an inorganic ion of an addition salt, a nitro or a nitroso DOAI514/631, Amidines (i.e., N=C-N)514/638, Nitrogen double bonded directly to carbon514/646Benzene ring containingExaminersPrimary: Nutter, Nathan M.Attorney, Agent or FirmInternational ClassesA61K 031/415A61K 031/505 A01N 043/54 A01N 043/58 AbstractA method for inhibiting tumor growth rate using creatine or creatine analogs is described. The creatine or creatine analogs are administered to subjects such that tumor growth rate is inhibited. Pharmaceutical compositions containing the creatine or creatine analogs and packaged products also are described.Field of SearchHetero ring is seven-membered consisting of two nitrogens and five carbon atomsNitrogen bonded directly to the 1,3-diazine at 2-position by a single bond 1,3-diazoles Divalent chalcogen or acyclic nitrogen double bonded directly to ring carbon of the diazole ring, or tautomeric equivalent Imidazoles Radical -XH acid, or anhydride, acid halide or salt thereof (X is chalcogen) DOAI Nitrogen other than as nitro or nitroso nonionically bonded RC(=O)N containing (i.e., carboxamide) (R is C or H) Plural nitrogens nonionically bonded Nitrogen containing other than solely as a nitrogen in an inorganic ion of an addition salt, a nitro or a nitroso DOAI Amidines (i.e., N=C-N) Nitrogen double bonded directly to carbon Benzene ring containing | |
