Method of selectively inhibiting prostaglandin G/H synthase-2
Patent 5571825 Issued on November 5, 1996. Estimated Expiration Date: 
March 31, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
March 31, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3558640 New benzhydrysulphinyl derivatives Acetic acid derivatives Halogenobenzhydrylsulfinylacetohydroxamic acids Benzhydryl compounds as herbicide antidotes Substituted bicyclic bis-aryl compounds exhibiting selective leukotriene B4 antagonist activity, their preparation and use in pharmaceutical compositions Patent #: 5366982 Inventors
ApplicationNo. 414394 filed on 03/31/1995US Classes:514/332, Plural six-membered hetero rings consisting of one nitrogen and five carbon atoms514/335, Chalcogen bonded directly to a ring carbon of the six-membered hetero ring514/437, Tricyclo ring system having the hetero ring as one of the cyclos514/444, Additional hetero ring514/455, Chalcogen bonded directly to ring carbon of the hetero ring514/461, The hetero ring is five-membered514/471, Nitrogen containing514/472, The nitrogen bonded directly to the hetero ring514/473, Chalcogen bonded directly to the hetero ring514/530, Z contains a cyclopentyl or cyclopentene ring514/532, Z-C(=O)-O-Y, wherein Z contains a benzene ring514/538, Nitrogen bonded to carbon in Z moiety514/539Plural separated benzene rings in Z moietyExaminersPrimary: Cintins, Marianne M.Assistant: Jarvis, William R. A. Attorney, Agent or FirmForeign Patent References
International ClassesA61K 031/44A61K 031/38 A61K 031/34 A61K 031/235 A61K 031/24 A61K 031/215 A61K 031/35 AbstractThe present invention provides a method of selectively inhibiting prostaglandin G/H synthase-2 that comprises administering to a patient in need of such inhibition an inhibiting amount of a compound having the Formula I, II or III ##STR1## wherein the R groups and heterocycles are defined in the disclosure.Other References
Field of SearchZ-C(=O)-O-Y, wherein Z contains a benzene ringNitrogen bonded to carbon in Z moiety Plural separated benzene rings in Z moiety Z contains a cyclopentyl or cyclopentene ring Chalcogen bonded directly to ring carbon of the hetero ring Tricyclo ring system having the hetero ring as one of the cyclos Plural six-membered hetero rings consisting of one nitrogen and five carbon atoms Chalcogen bonded directly to a ring carbon of the six-membered hetero ring Additional hetero ring Nitrogen containing The nitrogen bonded directly to the hetero ring Chalcogen bonded directly to the hetero ring The hetero ring is five-membered | |
