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Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids

Patent 5571536 Issued on November 5, 1996. Estimated Expiration Date: Icon_subject February 6, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Surface modified drug nanoparticles
Patent #: 5145684
Issued on: 09/08/1992
Inventor: Liversidge, et al.

Hydrophobic drug delivery systems Patent #: 5430021
Issued on: 07/04/1995
Inventor: Rudnic, et al.

Inventors

Application

No. 384057 filed on 02/06/1995

US Classes:

424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/450, Liposomes424/495, Ethyl cellulose424/498, Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof424/499, Contains proteins or derivative or polysaccharides or derivative514/772.1, Aftertreated solid synthetic organic polymer (e.g., grafting, blocking, etc.)514/937, DISPERSION OR EMULSION514/938, Oil-water type514/951POWDERS, GRANULES OR PARTICLES OF SPECIFIED MESH OR PARTICLE SIZE

Examiners

Primary: Page, Thurman K.
Assistant: Howard, Sharon

Attorney, Agent or Firm

International Class

A61K 009/14

Abstract

Nanoparticulate crystalline drug substances formulated in an aqueos phase emulsified in oil, are able to be made at less than 1000 nm size and provide increased bioavailability and lymphatic uptake following oral administration.

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