U.S. patents available from 1976 to present.
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Polyalkylene block copolymers as surface modifiers for nanoparticles

Patent 5565188 Issued on October 15, 1996. Estimated Expiration Date: Icon_subject February 24, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Preparing capped polyoxyalkylene polyols
Patent #: 4587365
Issued on: 05/06/1986
Inventor: Anchor

Ion conductors
Patent #: 5041346
Issued on: 08/20/1991
Inventor: Giles

Surface modified drug nanoparticles
Patent #: 5145684
Issued on: 09/08/1992
Inventor: Liversidge, et al.

Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants Patent #: 5326552
Issued on: 07/05/1994
Inventor: Na, et al.

Inventors

Application

No. 393972 filed on 02/24/1995

US Classes:

424/9.411, Polymer containing (e.g., polypeptide, synthetic resin, etc.)424/9.4, X-ray contrast imaging agent (e.g., computed tomography, angiography, etc.)424/9.45, Halogenated benzene ring containing424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/495, Ethyl cellulose424/499, Contains proteins or derivative or polysaccharides or derivative514/718, Plural oxygens514/975CHARACTERIZED BY THE DESIGNATED SURFACTANT USED

Examiners

Primary: Krass, Frederick

Attorney, Agent or Firm

International Class

A61K 009/14

Abstract

There is disclosed a composition containing nanoparticles having a surface modifier wherein the surface modifier is a block copolymer containing one or more polyoxyethylene blocks and one or more polyoxy(higher alkylene) blocks wherein at least some of the blocks are linked together by a linking group characterized in that the linking group is an oxymethylene group.

Other References

  • Chemical Abstracts 117:151640, "High Molecular Weight Polyetherpolyols
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