Patent ReferencesMedicaments potentiated with phenyl alkanols Method and composition for topically treating anorectal or other dermal wounds Bioadhesive pharmaceutical carrier Compositions and methods of treating hemorrhoids and wounds Patent #: 5196405 InventorsApplicationNo. 392045 filed on 02/22/1995US Classes:514/305, Quinuclidines (including unsaturation)514/312, Chalcogen attached directly to the six-membered hetero ring by nonionic bonding514/535, The nitrogen of the Z radical is directly bonded to a benzene ring which is directly bonded to the C(=O) group514/567, Benzene ring nonionically bonded514/568, Benzene ring nonionically bonded514/617, R contains benzene ring514/622, C-O- group in R514/652, Alkanol group only between the amino nitrogen and an ether oxygen which is bonded directly to the aryl ring or aryl ring system (i.e., aryloxy alkanol amines)514/653, Hydroxy, bonded directly to carbon, attached directly or indirectly to the acyclic carbon or chain by acyclic nonionic bonding (e.g., beta hydroxy phenethylamines, etc.)514/816, ANESTHETIC, GENERAL514/817, ANESTHETIC, TOPICAL514/818, ANESTHETIC, LOCAL514/944GELExaminersPrimary: Rollins, John W.Attorney, Agent or FirmInternational ClassesA61K 031/44A61K 031/47 A61K 031/24 A61K 031/195 AbstractThe present invention provides a topical anesthetic gel composition, comprising: (a) one or more topical anesthetic agents; (b) an adrenergic sympathomimetic compound; and (c) a pharmaceutical gel component. The present invention also provides a topical anesthetic gel composition, comprising: (a) tetracaine HCl, wherein said tetracaine HCl is contained in said composition in an amount of from about 0.01% to about 1.0% by weight, based upon the total weight of said composition; (b) epinephrine HCl topical solution, wherein said epinephrine HCl is contained in said composition in an amount of from about 0.04% to about 0.1% by weight, based upon the total weight of said composition; (c) cocaine HCl, wherein said cocaine HCl is contained in said composition in an amount of from about 3.0% to about 12.0% by weight, based upon the total weight of said composition; and (d) GELFOAM.RTM., wherein said Gelfoam.RTM. is contained in said composition in an amount of from about 6.0% to about 9.0% by weight, based upon the total weight of said composition. Further provided are other topical anesthetic compositions.Other References
Field of SearchANESTHETIC, TOPICALGEL The nitrogen of the Z radical is directly bonded to a benzene ring which is directly bonded to the C(=O) group R contains benzene ring Benzene ring nonionically bonded Chalcogen attached directly to the six-membered hetero ring by nonionic bonding Quinuclidines (including unsaturation) C-O- group in R Alkanol group only between the amino nitrogen and an ether oxygen which is bonded directly to the aryl ring or aryl ring system (i.e., aryloxy alkanol amines) Hydroxy, bonded directly to carbon, attached directly or indirectly to the acyclic carbon or chain by acyclic nonionic bonding (e.g., beta hydroxy phenethylamines, etc.) Benzene ring nonionically bonded ANESTHETIC, GENERAL ANESTHETIC, LOCAL | |