U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

3,3-diphenylpropylamines, their use and preparation

Patent 5559269 Issued on September 24, 1996. Estimated Expiration Date: Icon_subject May 5, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3-Aryloxy-1-(2- or 4-iminodihydro-1-pyridyl)-2-propanol antiarrhythmic compounds Patent #: 4139537
Issued on: 02/13/1979
Inventor: Diamond ,   et al.

Inventors

Assignee

Application

No. 432113 filed on 05/05/1995

US Classes:

564/443Hydroxy, bonded directly to carbon, or ether containing (H of -OH may be replaced by a substituted or unsubstituted ammonium ion or a Group IA or IIA light metal)

Examiners

Primary: Hamilton, III, Thomas

Attorney, Agent or Firm

Foreign Patent References

  • 1216318 DE. 11/13/1962
  • 1169944 GB. 11/13/1969
  • 1169945 GB. 11/13/1969
  • 89/06644 WO. 07/13/1989
  • WO94/11337 WO. 05/13/1994

International Class

A61K 031/135

Foreign Application Priority Data

1992-11-06 SE

Abstract

The invention relates to 3,3-diphenylpropylamines of formula (I), wherein R1 signifies hydrogen or methyl, R2 and R3 independently signify hydrogen, methyl, methoxy, hydroxy, carbamoyl, sulphamoyl or halogen, and X represents a tertiary amino group of formula (II), wherein R4 and R5 signify non-aromatic hydrocarbyl groups, which may be the same or different and which together contain at least three carbon atoms, and wherein R4 and R5 may form a ring together with the amine nitrogen, their salts with physiologically acceptable acids and, when the compounds can be in the form of optical isomers, the racemic mixture and the individual enantiomers. The invention also relates to methods for their preparation, pharmaceutical compositions containing the novel compounds, and the use of the compounds for preparing drugs ##STR1##

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