U.S. patents available from 1976 to present.
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Methods and apparatus for performing diagnostic and therapeutic ultrasound simultaneously

Patent 5558092 Issued on September 24, 1996. Estimated Expiration Date: Icon_subject June 6, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3672210

3735755

Linear array ultrasonic transducer
Patent #: 3936791
Issued on: 02/03/1976
Inventor: Kossoff

Linear array ultrasonic transducer
Patent #: 4385255
Issued on: 05/24/1983
Inventor: Yamaguchi ,   et al.

Carrier liquid solutions for the production of gas microbubbles, preparation thereof, and use thereof as contrast medium for ultrasonic diagnostics
Patent #: 4466442
Issued on: 08/21/1984
Inventor: Hilmann ,   et al.

Ultrasonic diagnostic and therapeutic transducer assembly and method for using
Patent #: 4484569
Issued on: 11/27/1984
Inventor: Driller ,   et al.

Dual function ultrasonic transducer assembly
Patent #: 4492120
Issued on: 01/08/1985
Inventor: Lewis ,   et al.

Device for localized heating of biological tissues
Patent #: 4586512
Issued on: 05/06/1986
Inventor: Do-huu ,   et al.

Ultrasound hyperthermia apparatus
Patent #: 4620546
Issued on: 11/04/1986
Inventor: Aida ,   et al.

Ultra sound hyperthermia device
Patent #: 4646756
Issued on: 03/03/1987
Inventor: Watmough ,   et al.

More ...

Inventors

Application

No. 468052 filed on 06/06/1995

US Classes:

600/439, With therapeutic device601/2, Ultrasonic601/3Hyperthermia

Examiners

Primary: Jaworski, Francis J.

Attorney, Agent or Firm

Foreign Patent References

  • 0351610 EP. 01/13/1990
  • 4205030 DE. 09/13/1992
  • WO80/02365 WO. 11/13/1980
  • WO92/17212 WO. 10/13/1992
  • WO92/21382 WO. 12/13/1992
  • WO94/28873 WO. 12/13/1994

International Classes

A61B 008/00
A61F 007/00
A61H 001/00

Abstract

Methods and apparatus for performing diagnostic ultrasound simultaneously with the application of therapeutic ultrasonic waves are disclosed. The methods and apparatus are particularly advantageous in performing ultrasonic imaging of a region of a patient while simultaneously applying therapeutic ultrasonic waves to the region for the purpose of rupturing vesicles administered to that region for purposes such as enhanced cavitation or the targeted release of a bioactive agent into the region. An operator is able to monitor the rupture of vesicles in real time.

Other References

  • Dickinson, R., "An Ultrasound System for Local Hyperthermia Using Scanned Focused Transducers", IEEE Transactions on Biomedical Engineering 1984, BME-31(1), 120-125
  • Duck, F. and Starritt, "A Study of the Heating Capabilities of Diagnostic Ultrasound Beams", Ultrasound in Med. & Biol. 1994, 20(5), 481-492
  • Fessenden, P. et al., "Experience with a Multitransducer Ultrasound System for Localized Hyperthermia of Deep Tissues", IEEE Transactions on Biomedical Engineering 1994, BME-31(1), 126-135
  • Frederiksen, F., "Guidelines for Characterization of Ultrasound Transducers", Ultrasonics 1992, 30(2), 119-121
  • Gautherie, M., ed., "Ultrasound Hyperthermia: Summary Proceedings of COMAC-BME Workshop", with contributing authors Hynynen, ter Haar and Watmough, Ultrasonics 1992, 30(2), 113-118
  • Hahn, G., "Hyperthermia for the Engineer: A Short Biological Primer", IEEE Transactions on Biomedical Engineering 1984, BME-31(1), 3-8
  • Hand, J. W., "III. Control of Ultrasound Hyperthermia Treatment. Thermometry in Ultrasonic Fields", Ultrasonics 1992, 30(2), 125-128
  • Hekkenberg, R. T. et al., "Development of Standard Measurement Methods for Essential Properties of Ultrasound Therapy Equipment", Ultrasound in Med. & Biol. 1994, 20(1), 83-98
  • Hinders, M. K. et al., "An Analytic Solution for Energy Deposition in Model Spherical Tumours Undergoing Ultrasound-hperthermia Treatments", Phys. Med. Biol. 1994, 39, 107-132
  • Hynynen, K., "Acoustic Power Calibrations of Cylindrical Intracavitary Ultrasound Hyperthermia Applicators", Med. Phys. 1993, 20(1), 129-134
  • Kazys, R. and Svilainis, "Analysis of Adaptive Imaging Algorithms for Ultrasonic Non-destructive Testing", Ultrasonics 1995, 33(1), 19-30
  • Lagendijk, J., "IV. Thermal Modelling and Treatment Planning. Thermal Modelling and Treatment Planning for Scanned Focused Ultrasound", Ultrasonics 1992, 30(2), 134-135
  • Ozyar, M. and Koymen, "Non-invasive Method for in situ Estimation of Intensity Using Non-linear Effects in Ultrasound Hyperthermia", Ultrasonics 1992, 30(2), 123-124
  • Frey, P. et al., "Three-dimensional Characterization of Ultrasonic Fields for Hyperthermia Treaments", Ultrasonics 1992, 30(2), 121-123
  • Lovejoy, A. et al., "A Novel 8-bit Ultrasound Phased-array Controller for Hyperthermia Applications", Ultrasonics 1995, 33(1), 69-73
  • Lu, J.-Y. et al., "Biomedical Ultrasound Beam Forming", Ultrasound in Med. & Biol. 1994, 20(5), 403-428
  • Miller, D. L., "Ultrasonic Detection of Resonant Cavitation Bubbles in a Flow Tube by their Second-harmonic Emissions", Ultrasonics 1981, 217-224
  • Roy, R. et al., "An Acoustic Backscattering Technique for the Detection of Transient Cavitation Produced by Microsecond Pulses of Ultrasound", J. Acoust. Soc. Am. 1990, 87(6), 2451-2458
  • Saitoh, S. et al., "A Dual Frequency Ultrasonic Probe for Medical Applications", IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 1995, 42(2), 294-300
  • Savakus, H. P. et al., "PZT-Epoxy Piezoelectric Transducers: A Simplified Fabrication Procedure", Mat. Res. Bull. 1981, 16, 677-680
  • Song, C. et al., "Implication of Blood Flow in Hyperthermic Treatment of Tumors", IEEE Transactions on Biomed. Engineering 1984, BME-31(1), 9-15
  • Vernon, C. C. et al., "Scanned Focused Ultrasound Hyperthermia Using the Sonotherm 6500 System", Ultrasonics 1992, 30(2), 141-143
  • Wu, J. et al., "Effect of Acoustic Streaming on Ultrasonic Heating", Ultrasound in Med. & Biol. 1994, 20(2), 195-201
  • Gautherie, M. and Frey, "Toward Clinical Treatment Planning for Ultrasound Hyperthermia", Ultrasonics 1992, 30(2), 135-137
  • Nguyen, M. T. and Faust, "Possibilities and Limitations of Temperature Monitoring Using Ultrasound Techniques", Ultrasonics 1992, 30(2), 128-131
  • Nadi, M. et al., "Ultrasound Thermography: Theoretical Aspects and Feasibility", Ultrasonics 1992, 30(2), 131-133
  • Acoustic Imaging; AI5200; Convex Curved Linear Array Ultrasound Transducers Operator's Manual, Nov. 20, 1989, 4700-0003-1C, p.
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