Inhibiting the development of tolerance to and/or dependence on an addictive substance
Patent 5556838 Issued on September 17, 1996. Estimated Expiration Date: 
May 19, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 19, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.InventorsAssigneeApplicationNo. 245970 filed on 05/19/1994US Classes:514/25, O-glycoside514/216, Two of the cyclos share at least three ring carbons (i.e., bridged)514/223.5, With additional active ingredient514/224.5, At least three cyclos in the polycyclo ring system514/225.5, The hetero ring is monocyclic piperidine514/231.2, Morpholines (i.e., fully hydrogenated 1,4- oxazines)514/282, One of the five cyclos is five-membered and includes ring chalcogen (e.g., codeine, morphine, etc.)514/304, Tropanes (including nor or dehydro form)514/305, Quinuclidines (including unsaturation)514/306, Quinolizines (including hydrogenated)514/307, Isoquinolines (including hydrogenated)514/812NarcoticExaminersPrimary: Criares, Theodore J.Attorney, Agent or FirmInternational ClassesA61K 031/70A61K 031/54 A61K 031/44 A61K 031/445 AbstractNontoxic substances that block the N-methyl-D-aspartate (NMDA) receptor, e.g., a morphinan such as dextromethorphan or dextrorphan, or that block a major intracellular consequence of NMDA-receptor activation, e.g., a ganglioside such as GM1 or GT1b, a phenothiazine such as trifluoperazine or a naphthalenesulfonamide such as N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, inhibit the development of tolerance to and/or dependence on addictive drugs, e.g., narcotic analgesics such as morphine, codeine, etc.Other References
Field of SearchO-glycosideTropanes (including nor or dehydro form) Quinuclidines (including unsaturation) Quinolizines (including hydrogenated) Isoquinolines (including hydrogenated) Two of the cyclos share at least three ring carbons (i.e., bridged) With additional active ingredient The hetero ring is monocyclic piperidine At least three cyclos in the polycyclo ring system One of the five cyclos is five-membered and includes ring chalcogen (e.g., codeine, morphine, etc.) Morpholines (i.e., fully hydrogenated 1,4- oxazines) Narcotic | |
