Surface modified NSAID nanoparticles
March 13, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 2996433 3192118 Process for the preparation of alkyl and aryl esters of 3'-substituted and 2', 3'-disubstituted 2-anilino-3-pyridinecarboxylic acids Biological materials Method for making uniformly sized particles from water-insoluble organic compounds Liquid oral pharmaceutical compositions of non-steroidal anti-inflammatory drugs Pharmaceutical delivery systems Central stitch controlling apparatus for circular knitting machine Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant InventorsApplicationNo. 402662 filed on 03/13/1995US Classes:424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/450, Liposomes424/495, Ethyl cellulose424/499Contains proteins or derivative or polysaccharides or derivativeExaminersPrimary: Page, Thurman K.Assistant: Benston, William E. Jr. Attorney, Agent or FirmForeign Patent References
International ClassA61K 009/14AbstractDispersible particles consisting essentially of a crystalline NSAID having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 400 nm. Pharmaceutical compositions containing the particles exhibit reduced gastric irritation following oral administration and/or hastened onset of action.Other References
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