U.S. patents available from 1976 to present.
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Method and compositions for topical application to the skin of tocotrienol for prevention and/or treatment of skin damage

Patent 5545398 Issued on August 13, 1996. Estimated Expiration Date: Icon_subject December 21, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Cosmetic stick
Patent #: 4695452
Issued on: 09/22/1987
Inventor: Gannis ,   et al.

Method of and composition for the prevention of solar radiation exposure-induced formation of carcinogenic skin lipid degradation products Patent #: 4975272
Issued on: 12/04/1990
Inventor: Voyt

Inventor

Application

No. 361737 filed on 12/21/1994

US Classes:

424/59, TOPICAL SUN OR RADIATION SCREENING, OR TANNING PREPARATIONS514/456, Bicyclo ring system having the hetero ring as one of the cyclos (e.g., chromones, etc.)514/458, Tocopherols (e.g., vitamin E, etc.)514/474, Ascorbic acid or derivative (e.g., vitamin C, etc.)514/847Facial moisturizer

Examiners

Primary: Dodson, Shelley A.

Attorney, Agent or Firm

Foreign Patent References

  • 45-23634 JP 07/13/1970
  • 51-73137 JP 06/13/1976
  • 0116616 JP 06/13/1985
  • 0166618 JP 06/13/1985
  • 1152613 JP 07/13/1986
  • 4686628 SU 09/13/1875

International Class

A61K 007/42

Abstract

A method for the prevention and/or treatment of skin or hair damage, particularly inflammation and aging of skin and hair damage from sunlight and chemicals, in which a tocotrienol, a derivative thereof or a vitamin E preparation enriched with tocotrienol or a tocotrienol derivative, is topically applied to the exposed or affected skin or hair areas. A fat-soluble fatty acid ester of ascorbic acid such as palmityl ascorbate is preferably applied with the tocotrienol in association with a dermatologically acceptable carrier.

Other References

  • Derwent Abstract of EP92-917637, Jul. 30, 1992, Bonte et al
  • Derwent Abstract of JP86-28625, Feb. 12, 1986, arakawa
  • Derwent Abstract of JP61183206A, Aug. 15, 1986, Lion Corp
  • Chem-Abs., vol. 119:152113, Lane et al
  • Chem-Abs, vol. 115:68388, Junichi et al
  • Burton, G. W., et al., J. Am. Chem. Soc. 107: 7073-7065 (1985)
  • The Merck Index, 11th ed., entries 9417-9423 and 9931 (1989)
  • Nakano., M., et al., Biochim. Biophys. Acta 619: 274-286 (1980)
  • Serbinova, E., et al., Free Radical Biology & Med. 10: 263-275 (1991)
  • Wilson, R., Drug and Cosmetic Industry, 32-34, 38 and 68 (Aug., 1992
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