Did You Know...
...that several people are credited with the invention of the flush toilet? Most people have heard of Thomas Crapper (1837-1910), the sanitary engineer who invented the valve-and-siphon arrangement that made the modern toilet possible. Another claimant to "the throne" was British inventor Alexander Cumming who patented a toilet in 1775. Then there's a nameless Minoan (a native of ancient Crete) who lived 4,000 years ago who supposedly was ahead of his time and created the first flush toilet!
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US Patent 5544646 - Systems for the intrapulmonary delivery of aerosolized aqueous formulations
US Patent Issued on August 13, 1996
Estimated Patent Expiration Date:
May 20, 2014Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Estimated Patent Expiration Date:
May 20, 2014Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractA disposable package, tape, and cassette are provided which makes it possible to hold and disperse therefrom liquid, flowable formulations including aqueous formulations (solutions or dispersions with particles less than 0.25 microns in diameter) of a pharmaceutically active drug. In one embodiment formulation is packaged in individual dosage unit containers which containers are preferably interconnected. The package is designed to be integrated into a cassette which can be loaded into a dispersing device capable of individually opening dosage unit containers and aerosolizing the contents through a porous membrane, into a mouth piece on the cassette, for delivery to a patient. In addition to and alongside of each porous membrane, the package may include one or more openings through which air is forced in order to aid in avoiding the accumulation of aerosolized particles. The package may be configured so that the formulation is held in a container not positioned directly vertical to and below the porous membrane, thus making it necessary to channel formulation horizontally to the porous membrane and making it possible to include a vibrating mechanism directly below a chamber covered by the porous membrane. Release of aerosolized drug is breath actuated based on simultaneous measurements of inspiratory flow and volume so as to provide for repeatable dosing of drug to the patient.Other References
| InventorsAssigneeApplicationNo. 247012 filed on 05/20/1994US Classes:128/200.14, LIQUID MEDICAMENT ATOMIZER OR SPRAYER128/200.22, Gas flow induced by expansion chamber device (e.g., piston/cylinder ram, squeeze bulb, etc.)128/203.12Means for mixing treating agent with respiratory gasField of Search128/200.14, LIQUID MEDICAMENT ATOMIZER OR SPRAYER128/200.22, Gas flow induced by expansion chamber device (e.g., piston/cylinder ram, squeeze bulb, etc.)128/203.12, Means for mixing treating agent with respiratory gas222/541.3, Closure or closure portion broken by pressure of container content222/541.4, About line or point of weakness206/531, Structure for "press-out" of content unit206/532With rupture means for accessExaminersPrimary: Lewis, Aaron J.Attorney, Agent or FirmUS Patent References3187748, 3565070, 3658059, 3757782, 3812854, 3814297, 3826413, 3861386, 3991304, Respiratory biofeedback and performance evaluation systemIssued on: 11/09/1976 Inventor: Hillsman 4090642, 4119096, Medical inhalation device for the treatment of diseases of the respiratory tract Issued on: 10/10/1978 Inventor: Drews4275840, Package for storing and spraying small amounts of liquids Issued on: 06/30/1981 Inventor: Staar4294407, Atomizer for fluids, preferably an inhalation device Issued on: 10/13/1981 Inventor: Reichl , et al.4334531, Inhalator Issued on: 06/15/1982 Inventor: Reichl , et al.4361401, Automatic sample deposition in flameless analysis Issued on: 11/30/1982 Inventor: Smith, Jr. , et al.4465234, Liquid atomizer including vibrator Issued on: 08/14/1984 Inventor: Maehara , et al.4484577, Drug delivery method and inhalation device therefor Issued on: 11/27/1984 Inventor: Sackner , et al.4533082, Piezoelectric oscillated nozzle Issued on: 08/06/1985 Inventor: Maehara , et al.4592348, Aerosol inhaler Issued on: 06/03/1986 Inventor: Waters, IV , et al.4604847, Medicine package, method of opening the package, and machine for performing the method Issued on: 08/12/1986 Inventor: Moulding, Jr. , et al.4627432, Devices for administering medicaments to patients Issued on: 12/09/1986 Inventor: Newell , et al.4648393, Breath activated medication spray Issued on: 03/10/1987 Inventor: Landis , et al.4677975, Method of dispensing and/or a dispenser Issued on: 07/07/1987 Inventor: Edgar , et al.4790305, Medication delivery system Issued on: 12/13/1988 Inventor: Zoltan , et al.4790479, Oscillating construction for an ultrasonic atomizer inhaler Issued on: 12/13/1988 Inventor: Matsumoto , et al.4803978, Apparatus for actuating an inhaler Issued on: 02/14/1989 Inventor: Johnson, IV , et al.4852582, Method and kit for measuring the effectiveness of bronchodilators Issued on: 08/01/1989 Inventor: Pell4877989, Ultrasonic pocket atomizer Issued on: 10/31/1989 Inventor: Drews, et al.4896832, Dispensing apparatus for metered quantities of pressurised fluid Issued on: 01/30/1990 Inventor: Howlett4926852, Medication delivery system phase one Issued on: 05/22/1990 Inventor: Zoltan, et al.5033463, Multi-dose inhaler for medicaments in powder form Issued on: 07/23/1991 Inventor: Cocozza5114240, Method and a device for preparing a mixture of a solid and a liquid component Issued on: 05/19/1992 Inventor: Kindt-Larsen, et al.5134993, Inhalator device, in particular a pocket inhalator Issued on: 08/04/1992 Inventor: van der Linden, et al.5152456, Dispensing apparatus having a perforate outlet member and a vibrating device Issued on: 10/06/1992 Inventor: Ross, et al.5348191Device for storage and dispensation of measured quantities of pasty materials and process for its embodiment Issued on: 09/20/1994 Inventor: Dekeyser Foreign Patent References
International ClassA61M 011/00 |
