Systems for the intrapulmonary delivery of aerosolized aqueous formulations
Patent 5544646 Issued on August 13, 1996. Estimated Expiration Date: 
May 20, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 20, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3187748 3565070 3658059 3757782 3812854 3814297 3826413 3861386 Respiratory biofeedback and performance evaluation system 4090642 InventorsAssigneeApplicationNo. 247012 filed on 05/20/1994US Classes:128/200.14, LIQUID MEDICAMENT ATOMIZER OR SPRAYER128/200.22, Gas flow induced by expansion chamber device (e.g., piston/cylinder ram, squeeze bulb, etc.)128/203.12Means for mixing treating agent with respiratory gasExaminersPrimary: Lewis, Aaron J.Attorney, Agent or FirmForeign Patent References
International ClassA61M 011/00AbstractA disposable package, tape, and cassette are provided which makes it possible to hold and disperse therefrom liquid, flowable formulations including aqueous formulations (solutions or dispersions with particles less than 0.25 microns in diameter) of a pharmaceutically active drug. In one embodiment formulation is packaged in individual dosage unit containers which containers are preferably interconnected. The package is designed to be integrated into a cassette which can be loaded into a dispersing device capable of individually opening dosage unit containers and aerosolizing the contents through a porous membrane, into a mouth piece on the cassette, for delivery to a patient. In addition to and alongside of each porous membrane, the package may include one or more openings through which air is forced in order to aid in avoiding the accumulation of aerosolized particles. The package may be configured so that the formulation is held in a container not positioned directly vertical to and below the porous membrane, thus making it necessary to channel formulation horizontally to the porous membrane and making it possible to include a vibrating mechanism directly below a chamber covered by the porous membrane. Release of aerosolized drug is breath actuated based on simultaneous measurements of inspiratory flow and volume so as to provide for repeatable dosing of drug to the patient.Other References
Field of SearchLIQUID MEDICAMENT ATOMIZER OR SPRAYERGas flow induced by expansion chamber device (e.g., piston/cylinder ram, squeeze bulb, etc.) Means for mixing treating agent with respiratory gas Closure or closure portion broken by pressure of container content About line or point of weakness Structure for "press-out" of content unit With rupture means for access | |
