U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Nasal administration of ketamine to manage pain

Patent 5543434 Issued on August 6, 1996. Estimated Expiration Date: Icon_subject February 25, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method for administering a dissociative, unconscious type of anesthesia
Patent #: 4334526
Issued on: 06/15/1982
Inventor: Hamacher

Methods and compositions for noninvasive administration of sedatives, analgesics, and anesthetics
Patent #: 4671953
Issued on: 06/09/1987
Inventor: Stanley ,   et al.

Pharmaceutical composition and method of intranasal administration
Patent #: 5112804
Issued on: 05/12/1992
Inventor: Kowarski

Compositions and methods of manufacture of compressed powder medicaments Patent #: 5132114
Issued on: 07/21/1992
Inventor: Stanley, et al.

Inventor

Application

No. 201756 filed on 02/25/1994

US Classes:

514/647Amino nitrogen and a ring bonded directly to the same ring and any other amino nitrogen in the compound is bonded directly to one of the rings

Examiners

Primary: Henley, III, Raymond
Assistant: Spivack, Phyllis G.

Attorney, Agent or Firm

Foreign Patent References

  • WO93/15737 WO. 08/13/1993

International Class

A61K 031/135

Abstract

The invention relates to self-management of pain on an outpatient basis comprising administering via a nasal route a dose of ketamine effective to alleviate pain to a subject suffering from pain.

Other References

  • Aldrete et al. (1988)Acta Anaesthesiol. Belg. 39 (No.3, Sup.2):95-6
  • (1990) West. J. Med. 153:311-2
  • (1980) J. Pediatr. Ophthalmol. Strabismus. 17:292-6
  • Trujillo and Akil. 1994. Brain Res. 633:178-88
  • Abram. 1993. Reg. Anesth. 18 (suppl):406-13
  • Louon et al. 1993. Br. J. Opthalmol. 77:529-30
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  • Stannard and Porter. 1993. Pain 54:227-30
  • Weksler et al. 1993. Can. J. Anaesthia 40:119-21
  • Adams and Hempelmann. 1990. Anasthesist 39:71-76. (English abstract only)
  • Oshima et al. 1990. Can. J. Anaesth. 37:385-92
  • Reich and Silvay. 1989. Can. J. Anaesth. 36:186-97
  • Sadove et al. 1971. Anesth. Analg. 50:452-57
  • Bovill and Dundee. 1971. Br. J. Anaesth. 43:496-94
  • Domino et al. 1965. Clin. Pharmacol. Ther. 6:279-91
  • Remington's Pharmaceutical Sciences, 16th ed. (1980) pp.1445, 155
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