U.S. patents available from 1976 to present.
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Therapeutic delivery systems related applications

Patent 5542935 Issued on August 6, 1996. Estimated Expiration Date: Icon_subject November 30, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3532500

3873564

Process for the preparation of liposomes
Patent #: 4089801
Issued on: 05/16/1978
Inventor: Schneider

Method for producing uniform particles
Patent #: 4162282
Issued on: 07/24/1979
Inventor: Fulwyler ,   et al.

Contrast media containing liposomes as carriers
Patent #: 4192859
Issued on: 03/11/1980
Inventor: Mackaness ,   et al.

Process for the preparation of liposomes in aqueous solution
Patent #: 4224179
Issued on: 09/23/1980
Inventor: Schneider

Process for the dehydration of a colloidal dispersion of lipsomes
Patent #: 4229360
Issued on: 10/21/1980
Inventor: Schneider ,   et al.

Ultrasonic image enhancement
Patent #: 4276885
Issued on: 07/07/1981
Inventor: Tickner ,   et al.

Lipid vesicles bearing carbohydrate surfaces as lymphatic directed vehicles for therapeutic and diagnostic substances
Patent #: 4310505
Issued on: 01/12/1982
Inventor: Baldeschwieler ,   et al.

Means of preparation and applications of liposomes containing high concentrations of entrapped ionic species
Patent #: 4310506
Issued on: 01/12/1982
Inventor: Baldeschwieler ,   et al.

More ...

Inventors

Application

No. 160232 filed on 11/30/1993

US Classes:

604/190, Having fluid filter424/450, Liposomes600/458Contrast enhancement

Examiners

Primary: Jaworski, Francis J.

Attorney, Agent or Firm

Foreign Patent References

  • 0107559 EP. 05/13/1984
  • 0231091 EP. 01/13/1987
  • 0324938 EP. 06/13/1988
  • 0272091 EP. 06/13/1988
  • 0338971 EP. 10/13/1989
  • 0361894 EP. 04/13/1990
  • 0216730 EP. 01/13/1991
  • 0458745A1 EP. 11/13/1991
  • 0314764B1 EP. 09/13/1992
  • 0554213A1 EP. 08/13/1993
  • 63-60943 JP. 03/13/1988
  • 2193095 GB. 02/13/1988
  • WO80/02365 WO. 11/13/1980
  • WO82/01642 WO. 05/13/1982
  • 8501161 WO. 09/13/1985
  • WO86/00238 WO. 01/13/1986
  • WO86/01103 WO. 02/13/1986
  • 8905040 WO. 02/13/1989
  • WO90/04943 WO. 05/13/1990
  • WO91/00086 WO. 01/13/1991
  • WO91/15244 WO. 10/13/1991
  • WO92/10166 WO. 06/13/1992
  • WO92/17212 WO. 10/13/1992
  • WO93/06869 WO. 04/13/1993
  • WO93/13809 WO. 07/13/1993
  • WO93/20802 WO. 10/13/1993
  • WO93/05819 WO. 11/13/1993

International Classes

A61M 005/00
A61B 008/00
A61K 009/127

Abstract

Therapeutic delivery systems comprising gaseous precursor-filled microspheres comprising a therapeutic are described. Methods for employing such microspheres in therapeutic delivery applications are also provided. Therapeutic delivery systems comprising gaseous precursor-filled liposomes having encapsulated therein a contrast agent or drug are preferred. Methods of and apparatus for preparing such liposomes and methods for employing such liposomes in therapeutic delivery applications are also disclosed.

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