U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Stabilized Pharmaceutical

Patent 5541231 Issued on July 30, 1996. Estimated Expiration Date: Icon_subject August 25, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Re33994

3819706

3885046

Compounds and methods of making same
Patent #: 4347176
Issued on: 08/31/1982
Inventor: Mehta

Compounds and methods of making them
Patent #: 4347177
Issued on: 08/31/1982
Inventor: Phillips

Compounds and methods of making
Patent #: 4347178
Issued on: 08/31/1982
Inventor: Findlay ,   et al.

Prolactin suppression in mammals
Patent #: 4347257
Issued on: 08/31/1982
Inventor: Stern

3H Labeled compounds
Patent #: 4347382
Issued on: 08/31/1982
Inventor: Scharver

Radioactive nuclide labeled propiophenone compounds
Patent #: 4355179
Issued on: 10/19/1982
Inventor: Findlay ,   et al.

Bupropion radioimmunoassay, and kit
Patent #: 4356165
Issued on: 10/26/1982
Inventor: Findlay ,   et al.

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Inventors

Application

No. 296252 filed on 08/25/1994

US Classes:

514/649, Amino nitrogen attached to aryl ring or aryl ring system by an acyclic carbon or acyclic chain514/769, DESIGNATED INORGANIC NONACTIVE INGREDIENT OR ELEMENTAL MATERIAL OTHER THAN WATER514/772DESIGNATED ORGANIC NONACTIVE INGREDIENT CONTAINING OTHER THAN HYDROCARBON

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

Foreign Patent References

  • 0171457A1 EP. 02/13/1986
  • 0467488A2 EP. 01/13/1992
  • WO92/19226 WO. 11/13/1992
  • WO94/04138 WO. 03/13/1994

International Class

A61K 031/135

Foreign Application Priority Data

1993-07-30 GB

Abstract

This application discloses a method of inhibiting degradation of the antidepressant bupropion hydrochloride in a solid pharmaceutical formulation, so that the pharmaceutical formulation will maintain at least 80% of its initial bupropion potency after one year.

Other References

  • Steven M. Walters; Influence of pH on Hydrolytic Decomposition of Diethylopropion Hydrochloride: Stability Studies on Drug Substance and Tablets Using High-Performance Liquid Ohromatography Journ. of Pharm. Sciences; vol. 69; No. 10; Oct. 1980; pp. 1206-120
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