U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Harmonic ultrasound imaging with microbubbles

Patent 5540909 Issued on July 30, 1996. Estimated Expiration Date: Icon_subject September 28, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Ultrasonic image enhancement
Patent #: 4276885
Issued on: 07/07/1981
Inventor: Tickner ,   et al.

Carrier liquid solutions for the production of gas microbubbles, preparation thereof, and use thereof as contrast medium for ultrasonic diagnostics
Patent #: 4466442
Issued on: 08/21/1984
Inventor: Hilmann ,   et al.

Two-component medication syringe assembly
Patent #: 4613326
Issued on: 09/23/1986
Inventor: Szwarc

Microbubble precursors and apparatus for their production and use
Patent #: 4657756
Issued on: 04/14/1987
Inventor: Rasor ,   et al.

Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures
Patent #: 4684479
Issued on: 08/04/1987
Inventor: D'Arrigo

Contrast agents for ultrasonic imaging
Patent #: 4718433
Issued on: 01/12/1988
Inventor: Feinstein

Ultrasonic imaging agent and method of preparation
Patent #: 4774958
Issued on: 10/04/1988
Inventor: Feinstein

Contrast medium for ultrasonic examinations and process for its preparation
Patent #: 4832941
Issued on: 05/23/1989
Inventor: Berwing ,   et al.

Concentrated stabilized microbubble-type ultrasonic imaging agent
Patent #: 4844882
Issued on: 07/04/1989
Inventor: Widder ,   et al.

Polymer composite for controlled release or membrane formation
Patent #: 4898734
Issued on: 02/06/1990
Inventor: Mathiowitz, et al.

More ...

Inventor

Application

No. 314074 filed on 09/28/1994

US Classes:

424/9.52, Stable gas bubbles containing or intentional solubilized gas containing424/9.51Liposome containing

Examiners

Primary: Raymond, Richard L.
Assistant: Cebulak, Mary C.

Attorney, Agent or Firm

Foreign Patent References

  • 3035189 AU. 08/13/1989
  • 123235B1 EP. 10/13/1984
  • 131540A2 EP. 01/13/1985
  • 231091A1 EP. 08/13/1987
  • 0230091 EP. 08/13/1987
  • 0279379 EP. 08/13/1988
  • 586875A1 EP. 02/13/1989
  • 320433A3 EP. 06/13/1989
  • 0357164 EP. 03/13/1990
  • 0359246 EP. 03/13/1990
  • 05542123 EP. 08/13/1993
  • 606613A1 EP. 07/13/1994
  • 0633030A1 EP. 07/13/1994
  • 0458745 EP. 09/13/1994
  • 59-67229 JP. 04/13/1984
  • 8905160 WO. 06/13/1989
  • 9109629 WO. 07/13/1991
  • 9112823 WO. 09/13/1991
  • 9115999 WO. 10/13/1991
  • 9222247 WO. 12/13/1992
  • 9300930 WO. 01/13/1993
  • 9302712 WO. 02/13/1993
  • 9301712 WO. 02/13/1993
  • 9303671 WO. 03/13/1993
  • 9306869 WO. 04/13/1993
  • 9305819 WO. 04/13/1993
  • 9325242 WO. 12/13/1993
  • 9401140 WO. 01/13/1994
  • 9406477 WO. 03/13/1994
  • 9408707 WO. 04/13/1994
  • 9409703 WO. 05/13/1994
  • 9409829 WO. 05/13/1994
  • 9416738 WO. 08/13/1994
  • 9421175 WO. 09/13/1994
  • 9428797 WO. 12/13/1994
  • 9428939 WO. 12/13/1994

International Class

A61K 049/00

Abstract

A method for ultrasonic harmonic imaging is disclosed, which uses microbubbles particularly selected for their properties of reradiating ultrasound energy at frequencies other than the exciting frequency.

Other References

  • "Principles and Recent Developments in Ultrasound Contrast Agents", N. de Jong, et al., Ultrasonics, 29:324-330, 1991
  • "First Ultrasound Contrast Agent Awaits OK from FDA", Greer, Advance for Radiologic Science Professionals, pp. 3-5, 1993
  • Acoustic Non-Linearity Due to Micro-Bubbles in Water Wesley & Safar, Acustica, 22: 177-182, 1969-70
  • Ultrasonic Disruption Alliger, Reprinted from American Laboratory, Oct. 1975
  • Demonstration of Nonlinear Acoustical Effects at Biomedical Frequencies and Intensities, Carstensen, et al., Ultrasound in Medicine & Biology, 6: 159-168, 1980
  • Textbook of Diagnostic Ultrasonography, Second Edition, by Sandra Hagen-Ansert, pp. 10-12, 1983
  • Application of ultrasonic processors, Berliner, III, Biotechnology Laboratory, 46-52, Mar. 1984
  • Ultrasound Enhancement of Tissues During the Capillary Phase of PFOB--100% Immediately Post Infusion, Mattrey, M.D., "Abstract, Association of University Radiologists" 35th Annual Meeting, Mar. 22-27, 1987
  • Perflurochemicals as US Contrast Agents for Tumor Imaging and Hepatosplenography: Preliminary Clinical Results, Mattrey, M.D., Radiology, 163: 339-343, 1987
  • Perflurooctylbromide: A New Contrast Agent for CT, Sonography, and MR Imaging, Mattrey, M.D., Manuscript 1988
  • Absorption and scatter of encapsulated gas filled microspheres: theoretical considerations and some measurements, de Jong, et al., Ultrasonics, 30: No. 3, 95-103, 1992
  • Simulated Capillary Blood Flow Measurement Using a Nonlinear Ultrasonic Contrast Agent, Schrope, et al., Ultrasonic Imaging, 14: 134-158, 199
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$16.95more info
 
Sign InRegister
Username  
Password   
forgot password?