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US Patent 5538993 - Certain tetrahydrocannabinol-7-oic acid derivatives
US Patent Issued on July 23, 1996
Estimated Patent Expiration Date:
February 7, 2014Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Estimated Patent Expiration Date:
February 7, 2014Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractThe invention relates to compounds of the formula ##STR1## having the (3S,4S) configuration and being essentially free of the (3R,4R) enantiomer, in which A--B indicates an optional 1(2) or 6(1) double bond, X is carboxy, carbalkoxy, or carboxamido, linked to the ring directly or through an alkylene linkage, G is halogen, alkyl, or oxy, and Y is alkyl, oxy, or oxyalkylene. The invention further relates to the synthesis of such compounds, and to pharmaceutical compositions and therapeutic methods in which such compounds may be employed.Other References
| InventorsAssigneeApplicationNo. 192923 filed on 02/07/1994US Classes:514/454, Tricyclo ring system having the hetero ring as one of the cyclos549/390Dibenzo(b,d)pyrans (including hydrogenated)Field of Search549/390, Dibenzo(b,d)pyrans (including hydrogenated)514/454Tricyclo ring system having the hetero ring as one of the cyclosExaminersPrimary: Richter, JohannAssistant: Peabody, John Attorney, Agent or FirmUS Patent References4179517, Novel tetrahydrocannabinol type compoundsIssued on: 12/18/1979 Inventor: Mechoulam , et al.4847290, Delta 1-thc-7-oic acid and analgesic and anti-inflammatory agents Issued on: 07/11/1989 Inventor: Burstein4876276, (3S-4S)-7-hydroxy-Ɗ6 -tetrahydrocannabinols Issued on: 10/24/1989 Inventor: Mechoulam, et al.5036014, Deuterated cannabinoids as standards for the analysis of tetrahydrocannabinol and its metabolites in biological fluids Issued on: 07/30/1991 Inventor: ElSohly, et al.5144030Fluorescene polarization immunoassay for tetrahydrocannabinoids Issued on: 09/01/1992 Inventor: Wang, et al. International ClassesA61K 031/35C07D 311/80 Foreign Application Priority Data1991-09-14 IL |
