Colonic drug delivery system
June 24, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesSustained release pharmaceutical compositions Compressed tablets for disintegration in the colon comprising an active ingredient containing nucleus coated with a first layer containing microcrystalline cellulose which is coated with an enteric organic polymer coating Novel controlled release formulations of tetracycline compounds Swellable pellets Targeted enternal delivery system Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine Patent #: 5326570 InventorsAssigneeApplicationNo. 265167 filed on 06/24/1994US Classes:424/479, Containing polysaccharide (e.g., sugar, etc.)424/480, Cellulose or derivative424/482, Containing solid synthetic polymers424/493, Containing polysaccharides (e.g., sugars)424/494, Cellulose derivatives424/495, Ethyl cellulose424/497Containing solid synthetic polymersExaminersPrimary: Page, Thurman K.Assistant: Spear, James M. Attorney, Agent or FirmForeign Patent References
International ClassesA61K 009/32A61K 009/36 A61K 009/58 A61K 009/62 AbstractA three component pharmaceutical formulation of one or more pharmacologically active substances such that greater than 80% of the pharmacologically active substance will be released in the large intestine. The first component comprises the pharmacologically active substance, microcrystalline cellulose, a pH-sensitive polymer, and optionally an osmotic agent. The second component is a delayed release coating, and the third component is an enteric coating.Other References
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