U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Passive transdermal device with controlled drug delivery

Patent 5533995 Issued on July 9, 1996. Estimated Expiration Date: Icon_subject May 13, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3923426

Implantable electrophoretic pump for ionic drugs and associated methods
Patent #: 4639244
Issued on: 01/27/1987
Inventor: Rizk ,   et al.

Method and apparatus for iontophoretic drug delivery
Patent #: 4722726
Issued on: 02/02/1988
Inventor: Sanderson ,   et al.

Cell for electrically controlled transdermal drug delivery
Patent #: 4731049
Issued on: 03/15/1988
Inventor: Parsi

Drug delivery device
Patent #: 4942883
Issued on: 07/24/1990
Inventor: Newman

Prolonged activity nicotine patch
Patent #: 4943435
Issued on: 07/24/1990
Inventor: Baker, et al.

Electrically controllable, non-occluding, body implantable drug delivery system
Patent #: 5041107
Issued on: 08/20/1991
Inventor: Heil, Jr.

Skin electrode construction and transdermal drug delivery device utilizing same
Patent #: 5156591
Issued on: 10/20/1992
Inventor: Gross, et al.

Electrolytic dispensing device
Patent #: 5186805
Issued on: 02/16/1993
Inventor: Gross, et al.

Transdermal drug delivery device Patent #: 5356632
Issued on: 10/18/1994
Inventor: Gross, et al.

Inventors

Assignee

Application

No. 244094 filed on 05/13/1994

US Classes:

604/890.1, CONTROLLED RELEASE THERAPEUTIC DEVICE OR SYSTEM424/449, Transdermal or percutaneous604/290Method of applying or removing material to or from body

Examiners

Primary: Green, Randall L.
Assistant: Bockelman, Mark

Attorney, Agent or Firm

Foreign Patent References

  • 0532451 EP 03/13/1993
  • 4040911 DE 06/13/1991
  • WO9004432 WO 05/13/1990

International Class

A61K 009/22

Foreign Application Priority Data

1991-11-13 IE

Abstract

A transdermal device for the controlled administration of a drug to the skin comprises a reservoir (12) for the drug and an electric circuit which includes an electrode system (13, 14) which is operable to actively transport the drug in a controlled manner from the reservoir (12) towards the skin for transport therethrough, the skin not being part of the electric circuit, and the drug passing through an electrode (13) of said electrode system (13, 14) during the active transport to the skin. The electrode (13) is disposed between the reservoir (12) for the drug and an optional transit chamber (15). The electrode (13) can be permeable to the drug or the electrode can function as a gate, being permeable to the drug in the open condition and less permeable to the drug in the closed condition. The operation of the gate can be determined by the composition or the structure of the electrode (13). The device achieves drug delivery rates comparable to those achieved with iontophoretic devices.

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