Low density microspheres and suspensions and their use as contrast agents for computed tomography and in other applications
Patent 5527521 Issued on June 18, 1996. Estimated Expiration Date: 
June 1, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 1, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3015128 3293114 3479811 3488714 3594326 3615972 3732172 Polymerization of styrene acrylonitrile expandable microspheres Method of preparing modified hollow, largely spherical particles by spray drying Thermoplastic expandable microsphere process and product InventorApplicationNo. 456738 filed on 06/01/1995US Classes:424/9.3, Magnetic imaging agent (e.g., NMR, MRI, MRS, etc.)424/9.4, X-ray contrast imaging agent (e.g., computed tomography, angiography, etc.)424/9.52, Stable gas bubbles containing or intentional solubilized gas containing424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/497, Containing solid synthetic polymers424/501Contains solid synthetic resinExaminersPrimary: Hollinden, Gary E.Attorney, Agent or FirmForeign Patent References
International ClassesA61B 005/055A61B 008/13 A61K 049/04 AbstractSubstantially homogeneous aqueous suspensions of low density microspheres are presented as contrast media for imaging the gastrointestinal tract and other body cavities using computed tomography. In one embodiment, the low density microspheres are gas-filled. With computed tomography, the contrast media serve to change the relative density of certain areas within the gastrointestinal tract and other body cavities, and improve the overall diagnostic efficacy of this imaging method.Other References
Field of SearchStable gas bubbles containing or intentional solubilized gas containingParticulate form (e.g., powders, granules, beads, microcapsules, and pellets) Containing solid synthetic polymers Contains solid synthetic resin Magnetic imaging agent (e.g., NMR, MRI, MRS, etc.) X-ray contrast imaging agent (e.g., computed tomography, angiography, etc.) Particulate matter (e.g., sphere, flake, etc.) | |
