Nanoparticulate nsaid compositions
Patent 5518738 Issued on May 21, 1996. Estimated Expiration Date: 
February 9, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 9, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesSurface modified drug nanoparticles Oral liquid compositions of non-steroidal anti-inflammatory drugs Patent #: 5183829 InventorsAssigneeApplicationNo. 385614 filed on 02/09/1995US Classes:424/493Containing polysaccharides (e.g., sugars)ExaminersPrimary: Cintins, Marianne M.Assistant: MacMillan, Keith D. Attorney, Agent or FirmForeign Patent References
International ClassA61K 009/16AbstractA composition comprising a crystalline NSAID having polyvinylpyrrolidone adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm, hygroscopic sugar and sodium lauryl sulfate exhibit greatly reduced gastric irritation following oral administration and/or hastened onset of action due to the substantial redispersion of the solid formulation to nanoparticles in gastric fluid.Other References
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