Did You Know...
...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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US Patent 5518738 - Nanoparticulate nsaid compositions
US Patent Issued on May 21, 1996
Estimated Patent Expiration Date:
February 9, 2015Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Estimated Patent Expiration Date:
February 9, 2015Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractA composition comprising a crystalline NSAID having polyvinylpyrrolidone adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm, hygroscopic sugar and sodium lauryl sulfate exhibit greatly reduced gastric irritation following oral administration and/or hastened onset of action due to the substantial redispersion of the solid formulation to nanoparticles in gastric fluid.Other References
| InventorsAssigneeApplicationNo. 385614 filed on 02/09/1995US Classes:424/493Containing polysaccharides (e.g., sugars)Field of Search514/570, Carboxy or salt thereof only attached indirectly to the benzene ring424/493Containing polysaccharides (e.g., sugars)ExaminersPrimary: Cintins, Marianne M.Assistant: MacMillan, Keith D. Attorney, Agent or FirmUS Patent References5145684, Surface modified drug nanoparticlesIssued on: 09/08/1992 Inventor: Liversidge, et al.5183829Oral liquid compositions of non-steroidal anti-inflammatory drugs Issued on: 02/02/1993 Inventor: Caldwell Foreign Patent References
International ClassA61K 009/16 |
