U.S. patents available from 1976 to present.
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Method for measuring internal information in scattering medium and apparatus for the same

Patent 5517987 Issued on May 21, 1996. Estimated Expiration Date: Icon_subject June 1, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method of and apparatus for measuring the inside information of substance with the use of light scattering
Patent #: 5057695
Issued on: 10/15/1991
Inventor: Hirao, et al.

Noninvasive measurement of hematocrit and hemoglobin content by differential optical analysis
Patent #: 5277181
Issued on: 01/11/1994
Inventor: Mendelson, et al.

Sensor, apparatus and method for non-invasive measurement of oxygen saturation
Patent #: 5285783
Issued on: 02/15/1994
Inventor: Secker

Arterial blood monitoring probe
Patent #: 5297548
Issued on: 03/29/1994
Inventor: Pologe

Absorption spectrum determining method and spectrometric measuring apparatus for light-diffusive object using the method
Patent #: 5333610
Issued on: 08/02/1994
Inventor: Hirao

Blood constituent determination based on differential spectral analysis Patent #: 5372135
Issued on: 12/13/1994
Inventor: Mendelson, et al.

Inventor

Assignee

Application

No. 252227 filed on 06/01/1994

US Classes:

600/328Hemoglobin

Examiners

Primary: Sykes, Angela D.
Assistant: Winakur, Eric F.

Attorney, Agent or Firm

Foreign Patent References

  • 64-88340 JP. 04/13/1989
  • 1174940 JP. 07/13/1989
  • 4110751 JP. 04/13/1992
  • 2228314 GB. 08/13/1990
  • 8912223 WO. 12/13/1989
  • 9004941 WO. 05/13/1990
  • 9201216 WO. 01/13/1992
  • 9221283 WO 12/13/1992

International Class

A61B 005/00

Foreign Application Priority Data

1993-06-02 JP

Abstract

A method of measuring internal information in a scattering medium, and an apparatus for the same of the present invention measure internal information in the scattering medium by measuring light diffused during propagation in the scattering medium while receiving the influence of the scattering and absorption, and performing arithmetic processing to the measured values. At this time, the three or more kinds of the detected signals (measured values) measured at three or more different kinds of distances between the light incident position and the photodetection point are processed by utilizing dependencies of the behavior of light diffused during propagation in the scattering medium and the resulting signal, that is, a photodetection signal on characteristics such as a scattering constituent, or an absorption constituent in the scattering medium and the concentration. The measured internal information is the absolute value of a scattering coefficient or a transport scattering coefficient of the scattering medium, and the information associated with a specified scattering constituent or a specified absorption constituent can be measured by processing the measured internal information.

Other References

  • Graaff et al, "Optical Properties of Human Dermis In Vitro and In Vivo", Applied Optics, vol. 32, No. 4, Feb. 1, 1993, pp. 435-447
  • Farrell et al, "A Diffusion Theory Model of Spatially Resolved, Steady-State Diffuse Reflectance for the Noninvasive Determination of Tissue Optical Properties In Vivo" Med. Physics, vol. 19, No. 4, Jul. 1992, pp. 879-888
  • Farrell et al, "The Use of a Neural Network to Determine Tissue Optical Properties From Spatially Resolved Diffuse Reflectance Measurements", Phys. Med. Biol., vol. 37, No. 12, 1192, pp. 2281-2286
  • Wilson et al, "Optical Reflectance and Transmittance of Tissues: Principles and Applications", IEEE Journal of Quantum Electronics, vol. 26, No. 12, Dec. 1990, pp. 2186-2199
  • I. Oda et al, "Non-Invasive Hemoglobin Oxygenation Monitor and Computed Tomography By NIR Spectrophotometry", pp. 284-293, SPIE, vol. 1431, 1991
  • M. S. Patterson et al, "Time-Resolved Reflectance and Transmittance for the Non-Invasive Measurement of Tissue Optical Properties", pp. 2331-2336, Applied Optics, vol. 28, No. 12, Jun. 15, 1989
  • M. S. Patterson et al. "Applications of Time-Resolved Light Scattering Measurements to Photodynamic Therapy Dosimetry", pp. 62-75, SPIE, vol. 1203, 1990
  • E. M. Sevick et al, "Time-Dependent Photon Migration Imaging", pp. 273-283, SPIE, vol. 1599, 199
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