Use of ascorbic acid to reduce irritation of topically applied active ingredients
Patent 5516793 Issued on May 14, 1996. Estimated Expiration Date: 
June 29, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 29, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesCosmetic preparation incorporating stabilized ascorbic acid Stable ascorbic acid compositions Patent #: 5140043 InventorAssigneeApplicationNo. 268658 filed on 06/29/1994US Classes:514/474Ascorbic acid or derivative (e.g., vitamin C, etc.)ExaminersPrimary: Fay, ZohrehAttorney, Agent or FirmInternational ClassA61K 031/34AbstractThe use of an effective amount of ascorbic acid (Vitamin C) or one or more of its derivatives, has been found to decrease skin irritation caused by the topical administration of an active ingredient for treating a skin condition. Examples of the active ingredient include -hydroxy acids, ଲ-hydroxy acids, keto acids, benzoyl peroxide, retinol (Vitamin A) , retinoic acid, retinal, Vitamin A2, Vitamin A epoxide, lactamides and quaternary ammonium lactates, C4-12 hydroxylated carboxylic acids, sulfur, resorcinol and salicylic acid, and various derivatives thereof. The ascorbic acid (or its derivatives) is present in effective amounts from about 0.5% to about 25% by weight. It is provided by topical application of a separate solution or by admixture with a cosmetically or pharmaceutically acceptable vehicle for the active ingredient.Other References
Field of SearchAscorbic acid or derivative (e.g., vitamin C, etc.) | |
