Process for preparing therapeutic compositions containing nanoparticles

Patent 5510118 Issued on April 23, 1996. Estimated Expiration Date:

February 14, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

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Inventors

Assignee

NanoSystems LLC

Application

No. 388092 filed on 02/14/1995

US Classes:

424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/488, Polysaccharides (e.g., cellulose, etc.)424/490Coated (e.g., microcapsules)

Examiners

Primary: Page, Thurman K.
Assistant: Benston, William E. Jr.

Attorney, Agent or Firm

Rudman & Balogh

International Class

A61K 009/14

Abstract

A process of preparing nanoparticulate drug substances comprising the steps of: preparing a premix of the drug substance and a surface modifier, and subjecting the premix to mechanical means to reduce the particle size of the drug substance, the mechanical means producing shear, impact, cavitation and attrition.

Other References

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