Spherical seed cores, spherical granules and process for production thereof
October 17, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3146168 3539380 3873694 Novel excipient and pharmaceutical composition containing the same Sugar-coated solid dosage forms Pharmaceutically preparation comprising a cardiac glycoside in combination with a polymer Colored medicinal tablet, natural color pigment and method for using the pigment in coloring food, drug and cosmetic products Easily-swallowed, powder-free and gastric-disintegrable aspirin tablet thinly-coated with hydroxypropyl methylcellulose and aqueous spray-coating preparation thereof Process for preparing solid unit dosage forms of ultra-low dose drugs Process for the preparation of activated pharmaceutical compositions InventorAssigneeApplicationNo. 325952 filed on 10/17/1994US Classes:427/2.21, Retarded or controlled-release layer produced (e.g., enteric)427/2.16, Retarded or controlled-release layer produced (e.g., enteric)427/2.19, Retarded or controlled-release layer produced (e.g., enteric)427/196, Plural direction application of coating materials or simultaneously applying particles and binder from different sources427/214Applying superposed diverse coatings or coating a coated baseExaminersPrimary: Dudash, DianaAttorney, Agent or FirmForeign Patent References
International ClassesA61K 047/38A61K 009/14 B05D 001/34 Foreign Application Priority Data1990-04-18 JPAbstractPharmacologically inactive spherical seed cores comprising at least 50% by weight of microcrystalline cellulose having an average degree of polymerization of 60 to 375, wherein the spherical seed cores have an average particle size of 100 to 1000 μm, a tapped bulk density of at least 0.65 g/ml, an aspect ratio of at least 0.7, a water absorption capacity of 0.5 to 1.5 ml/g, and a friability of no more than 1%; spherical granules comprising the spherical seed cores coated with a powdery layer comprising active ingredients and having an outer layer of coating provided on the powdery layer; and a process for the production of spherical granules, comprising the steps of coating the spherical seed cores with powder comprising active ingredients using an aqueous binding solution, spraying an aqueous solution or suspension of a coating agent thereon, and drying the resulting coated granules.Other References
Field of SearchRetarded or controlled-release layer produced (e.g., enteric)En masse rotating means employed (e.g., rotating pan, tumbling) Retarded or controlled-release layer produced (e.g., enteric) Retarded or controlled-release layer produced (e.g., enteric) Plural direction application of coating materials or simultaneously applying particles and binder from different sources Applying superposed diverse coatings or coating a coated base Ingredients supplied separately | |
