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AbstractA method of therapeutically administering certain BZ1 specific trifluorobenzodiazepines in order to maximize the BZ1 effects and minimize the BZ2 effects on the human central nervous system in order to maximize the anti-anxiety, anticonvulsant and hypnotic effects and minimize the ataxic and incoordination effects of the drug. Also, a method of sublingual administration of trifluorobenzodiazepines and certain other compounds, such as propoxyphene and nefazodone, in order to decrease unwanted metabolites.Other References
| InventorsApplicationNo. 321246 filed on 10/11/1994US Classes:514/254.05Plural nitrogens in the additional five-membered hetero ringExaminersPrimary: Criares, Theodore J.Attorney, Agent or FirmUS Patent References4613600Antidepressant 1,2,4-triazolone compoundsIssued on: 09/23/1986 Inventor: Gammans , et al. International ClassesA61K 031/495A61K 031/50 |