U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method of treating prostatic adenocarcinoma

Patent 5496556 Issued on March 5, 1996. Estimated Expiration Date: Icon_subject December 20, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Phosphonic acid substituted aromatic steroids as inhibitors of steroid 5-଱-reductase
Patent #: 4882319
Issued on: 11/21/1989
Inventor: Holt, et al.

Steroid 5-alpha-reductase inhibitors
Patent #: 4910226
Issued on: 03/20/1990
Inventor: Holt, et al.

Phosphinic acid substituted aromatic steroids as inhibitors of steroid 5-60 -reductase
Patent #: 4937237
Issued on: 06/26/1990
Inventor: Holt, et al.

Phosphonic acid substituted steroids as steroid 5଱-reductase inhibitors
Patent #: 4946834
Issued on: 08/07/1990
Inventor: Holt, et al.

Sulfonic acid substituted aromatic steroids as inhibitors of steroid 5-଱-reductase
Patent #: 4970205
Issued on: 11/13/1990
Inventor: Holt, et al.

Steriod 5-alpha-reductase inhibitors
Patent #: 5017568
Issued on: 05/21/1991
Inventor: Holt, et al.

7-keto or hydroxy 3,5-diene steroids as inhibitors of steroid 5-alpha reductase
Patent #: 5032586
Issued on: 07/16/1991
Inventor: Metcalf, et al.

11-keto or hydroxy 3,5-diene steroids as inhibitors of steriod 5-଱-reductase
Patent #: 5041433
Issued on: 08/20/1991
Inventor: Holt, et al.

Steroidal 3-acetic acid derivatives as 5-alpha-reductase inhibitors
Patent #: 5137882
Issued on: 08/11/1992
Inventor: Holt, et al.

Method of treating prostatic adenocarcinoma Patent #: 5300294
Issued on: 04/05/1994
Inventor: Johnson

Inventor

Assignee

Application

No. 170481 filed on 12/20/1993

US Classes:

424/423, Surgical implant or material424/451, Capsules (e.g., of gelatin, of chocolate, etc.)424/456, Gelatin424/464, Tablets, lozenges, or pills514/169, Cyclopentanohydrophenanthrene ring system DOAI514/172, Hetero ring containing514/173, Spiro ring system514/177, Oxygen double bonded to a ring carbon of the cyclopentanohydrophenanthrene ring system514/178, Oxygen single bonded to a ring carbon of the cyclopentanohydrophenanthrene ring system514/179, Modified C-ring (except methyl in 13-position) (e.g., double bond containing, substituted, etc.)514/180, 9-position substituted514/181, 21-position substituted514/182, Oxygen single bonded to a ring carbon of the cyclopentanohydrophenanthrene ring system514/319, The additional ring is one of the cyclos in a polycyclo ring system514/428, Chalcogen bonded indirectly to the five-membered hetero ring by acyclic nonionic bonding514/462Spiro ring system

Examiners

Primary: Azpuru, Carlos

Attorney, Agent or Firm

Foreign Patent References

  • 0004949B1 EP. 04/13/1978
  • 200859 EP. 11/13/1986
  • 279010 EP. 08/13/1988
  • 0285383A2 EP. 10/13/1988
  • 414490A EP. 02/13/1991
  • 414491A EP. 02/13/1991
  • 9100733 WO. 01/13/1991

International Classes

A61K 009/20
A61K 009/48
A61K 031/56
A61K 031/58

Abstract

Invented is a Method of Treating Prostatic Adenocarcinoma by employing asteroid 5-଱-reductase inhibiting compound or a combination of steroid 5-଱-reductase inhibiting compounds.

Other References

  • J. Natl Cancer Inst; 74(2) pp. 475-486 (1985)
  • The Urologic Clinics of North America; vol. 18, No. 1 pp. 93-98 (1991)
  • Progress in Cancer Research Therapy; vol. 31, No. 2 pp. 477-489 (1984)
  • J. Med. Chem.; vol. 33, No. 3, pp. 937-942 (1990)
  • J. Med. Chem.; vol. 33, No. 3, pp. 943-950 (1990)
  • J. Steroid Biochem; vol. 34, Nos. 1-6, pp. 571-575 (1989)
  • The Prostate; 18, pp. 215-227 (1991)
  • J. Steroid Biochem; 24, pp. 887-886 (1986)
  • Bio Chemistry; 28, (1989)
  • Endocrinology, 117 No. 2, pp. 571-579 (1985)
  • Academic Press, Inc, CH 8 V, pp. 269-304 (1984
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