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଱-3 sialyltransferase

Patent 5494790 Issued on February 27, 1996. Estimated Expiration Date: Icon_subject September 20, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Process for controlling intracellular glycosylation of proteins Patent #: 5047335
Issued on: 09/10/1991
Inventor: Paulson, et al.

Inventors

Application

No. 309985 filed on 09/20/1994

US Classes:

435/6, Involving nucleic acid435/85, N-glycoside435/193, Transferase other than ribonuclease (2.)435/252.33, Escherichia (e.g., E. coli, etc.)435/320.1, VECTOR, PER SE (E.G., PLASMID, HYBRID PLASMID, COSMID, VIRAL VECTOR, BACTERIOPHAGE VECTOR, ETC.) BACTERIOPHAGE VECTOR, ETC.)536/23.2Encodes an enzyme

Examiners

Primary: Patterson, Charles L. Jr.

Attorney, Agent or Firm

Foreign Patent References

  • 475354 EP. 03/13/1992
  • WO91-12340 WO. 02/13/1991
  • WO91-06635 WO. 08/13/1991
  • 12340 WO. 08/13/1991

International Classes

C12Q 001/68
C12N 009/10
C12N 015/54

Foreign Application Priority Data

1991-12-17 JP

Abstract

There are provided a novel 댒→3 sialyltransferase expressed by a cloned gene from animal cells, a cDNA encoding the 댒→3 sialyltransferase, a method for detecting or suppressing the expression of an 댒→3 sialyltransferase by use of said cDNA, a recombinant vector containing said cDNA, a cell containing said vector, and their production processes.

Other References

  • Ripka, et al, Biochem. Biophys. Acfa., vol. 159, No. 2 (1989) 554-60
  • Paulson, et al., FASEB J., vol. 4, No. 7 (1990) A1862
  • Gillespie, et al., FASEB J., vol. 4, No. 7 (1990) A2068
  • Joziasse, et al., J. Biol. Chem., vol. 260, No. 8 (1985) 4941-51
  • Weinstein et al., J. Biol. Chem. vol. 262, No. 36 pp. 17735-17743 (1987)
  • Weinstein et al., J. Biol. Chem. vol. 257, No. 22 pp. 13835-13844 (1982)
  • Wen et al., J. Biol. Chem., vol. 267 (Oct. 1992) pp. 21011-21019
  • Kanani et al., Cancer Research, vol. 50 (Aug. 1990) pp. 5003-5007
  • Sadler et al., J. Biol. Chem., vol. 254, No. 11 (Jun. 1979) pp. 4434-4443
  • Saitoh et al., Cancer Research, vol. 51 (Jun. 1991) 2854-2862
  • Phillips et al., Science, vol. 250 (Nov. 1990) pp. 1130-1132
  • Sabesan et al. J. Am. Chem. Soc., vol. 108, No. 8 (1986) pp. 2068-208
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