U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Partial liquid breathing of fluorocarbons

Patent 5490498 Issued on February 13, 1996. Estimated Expiration Date: Icon_subject September 1, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Non-toxic brominated perfluorocarbons radiopaque agents
Patent #: 3975512
Issued on: 08/17/1976
Inventor: Long, Jr.

Natural pulmonary surfactant, method of preparation and pharamceutical compositions
Patent #: 5024995
Issued on: 06/18/1991
Inventor: Robertson, et al.

Lung cancer hyperthermia via ultrasound and/or convection with perfiuorochemical liquids Patent #: 5158536
Issued on: 10/27/1992
Inventor: Sekins, et al.

Inventors

Application

No. 299884 filed on 09/01/1994

US Classes:

128/203.12, Means for mixing treating agent with respiratory gas128/913BREATHABLE LIQUIDS

Examiners

Primary: Lewis, Aaron J.

Attorney, Agent or Firm

Foreign Patent References

  • 2245299 DE. 04/13/1973
  • 858824 SU. 08/13/1981
  • 1143420 SU. 03/13/1985
  • 9103267 WO. 03/13/1991

International Class

A61M 015/00

Abstract

The present invention includes a method for treating a patient in need of facilitated oxygen delivery through the lungs, additional lung surfactant, removal of material from inside the lung, or inflation of collapsed portions of the lung, comprising the step of introducing into the lung of the patient an effective therapeutic amount of a fluorocarbon liquid, the amount not exceeding the functional residual capacity of the lung of the patient upon exhalation taking into account any positive and expiratory pressure applied to the patient's lung. The method may also comprise the additional step of providing an oxygen-containing breathing gas to the patient while the fluorocarbon liquid is in the lung.

Other References

  • Greenspan, et al., "Liquid Ventilation Of Preterm Baby", Lancet, Nov. 4, 1989, p. 1095
  • Widjaja, et al., "Mechanical Properties Of Isolated Fetal Miniature Pig Lungs After Substitution . . . ", Res. Exp. Med., 188:425-432 (1988)
  • Waldrop, "The (Liquid) Breath Of Life", Science, 245:1043-1045
  • Richman, et al., "Lung Lavage With Oxygenated Fluorocarbon Improves Gas Exchange And Lung Compliance In Cats With Acute Lung Injury", 1990 World Conference on Lung Health, Category 26
  • Derwent-Information Service, file WPIL, accession no. 91-354366 {49}, Derwent Publications Ltd, London, GB, & CA,A2035492 (Sekins) 20 Sep. 1991, see the entire abstract
  • "Physiological Effects of Ventilation with Liquid Fluorocarbon at Controlled Temperatures", Shaffer et al.; Undersea Biomedical Research, vol. 11, #3, Sep. 1984
  • Reiss, J. G., Artificial Organs 8:34-56, 1984
  • Nakayama et al. Crit. Care Med. 19:926-933 (1991)
  • Ravenscraft et al., Crit. Care Med 19:916-925, (1991)
  • Richman et al. Abstract 1990, World Conference on Lung Health, Boston Mass
  • Rufer et al. Chest 66(Suppl.) 29S-30S (1974)
  • Shaffer et al. Pediat. Res. 10:227-231, (1976)
  • Shaffer et al. Chest Res. 17:303-306 (1983)
  • Curtis et al. Crti. Care Med. 19(2):225-230, (1991)
  • Curtis et al. J. Appl. Physiol. 68(6):2322-8 (1990)
  • Shaffer et al. Undersea Biomed. Res. 14:169-170 (1987)
  • Shaffer et al. J. Appl. Physiol. 36:208-213 (1974)
  • Merritt et al. Drugs 38(4):591-611, (1989)
  • Yokoyama et al. Artificial Organs 8(1):34-40, (1984
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