Multilayered controlled release pharmaceutical dosage form
Patent 5474786 Issued on December 12, 1995. Estimated Expiration Date: 
October 6, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
October 6, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesOral sustained-release drug compositions Sustained release diltiazem formulation Controlled release formulation for pharmaceutical compounds Controlled absorption diltiazem formulation for once daily administration Sustained release composition for oral administration of active ingredient Patent #: 5407686 InventorsAssigneeApplicationNo. 319186 filed on 10/06/1994US Classes:424/472, Layered unitary dosage forms424/458, Containing discrete coated particles pellets, granules, or beads424/461, Containing polysaccharide (e.g., cellulose sugars, etc.)424/462, Containing solid synthetic polymers424/469, Discrete particles in supporting matrix424/488, Polysaccharides (e.g., cellulose, etc.)424/490, Coated (e.g., microcapsules)424/494, Cellulose derivatives424/495, Ethyl cellulose424/497Containing solid synthetic polymersExaminersPrimary: Marquis, Melvyn I.Assistant: Hulina, Amy International ClassesA61K 009/54A61K 009/62 AbstractThis invention is directed to a multilayered controlled release pharmaceutical dosage form. More particularly the dosage form is adapted for water soluble drugs and comprises a plurality of coated particles wherein each has multiple layers about a core containing a drug active whereby the drug containing core and at least one other layer of drug active is overcoated with a controlled release barrier layer and preferably an outer layer of additional drug is adapted for immediate release to preferably provide one immediate releasing layer and at least two controlled releasing layers of a water soluble drug from the multilayered coated particle.Field of SearchCoated (e.g., microcapsules)Cellulose derivatives Ethyl cellulose Containing solid synthetic polymers Polysaccharides (e.g., cellulose, etc.) Discrete particles in supporting matrix Layered unitary dosage forms Containing discrete coated particles pellets, granules, or beads Containing polysaccharide (e.g., cellulose sugars, etc.) Containing solid synthetic polymers | |
