U.S. patents available from 1976 to present.
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Composition comprising a tramadol material and any of codeine, oxycodone or hydrocodone and their use

Patent 5468744 Issued on November 21, 1995. Estimated Expiration Date: Icon_subject June 30, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3652589

Inventors

Assignee

Application

No. 268382 filed on 06/30/1994

US Classes:

514/282, One of the five cyclos is five-membered and includes ring chalcogen (e.g., codeine, morphine, etc.)514/646Benzene ring containing

Examiners

Primary: Henley, III, Raymond
Assistant: Jarvis, William R. A.

Attorney, Agent or Firm

International Classes

A61K 031/485
A61K 031/135

Abstract

This invention relates to compositions comprising a tramadol material selected from the group consisting of tramadol, its stereoisomers and its pharmaceutically acceptable salts and either codeine or oxycodone, and their use in treating pain. When the components, i.e., tramadol materials and either of codeine or oxycodone, of the composition are within certain ratios of pharmacological effects of the compositions are superaddditive (synergistic).

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