U.S. patents available from 1976 to present.
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Intravascular stent and method

Patent 5464650 Issued on November 7, 1995. Estimated Expiration Date: Icon_subject April 26, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

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Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
Patent #: 4776337
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Endovascular stent and delivery system
Patent #: 4800882
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Intravascular radially expandable stent and method of implant
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Inventors

Assignee

Application

No. 052878 filed on 04/26/1993

US Classes:

427/2.3, Fluid barrier or fluid transporting product, other than merely absorbing (e.g., surgical glove, condom, lined diaper, membrane filter, IV tubing, cannula, dialysis membrane, urinary catheter)427/2.25, Liquid conveying (e.g., vascular, arterial, bile duct, urethra)427/2.28Device for creating or holding open an unnatural opening in a membrane or organ (e.g., syringe, scalpel, drainage tube)

Examiners

Primary: Dudash, Diana

Attorney, Agent or Firm

Foreign Patent References

  • 9013332 WO. 11/13/1990
  • 9112779 WO. 09/13/1991
  • 9116102 WO. 10/13/1991
  • 9117789 WO. 11/13/1991
  • 9118940 WO. 12/13/1991
  • 9215286 WO. 09/13/1992
  • 9306792 WO. 04/13/1993
  • 0566245 WO. 10/13/1993

International Classes

B05D 001/02
B05D 001/18
B05D 001/38

Abstract

A method for making an intravascular stent by applying to the body of a stent a solution which includes a solvent, a polymer dissolved in the solvent and a therapeutic substance dispersed in the solvent and then evaporating the solvent. The inclusion of a polymer in intimate contact with a drug on the stent allows the drug to be retained on the stent during expansion of the stent and also controls the administration of drug following implantation. The adhesion of the coating and the rate at which the drug is delivered can be controlled by the selection of an appropriate bioabsorbable or biostable polymer and the ratio of drug to polymer in the solution. By this method, drugs such as dexamethasone can be applied to a stent, retained on a stent during expansion of the stent and elute at a controlled rate.

Other References

  • "Seeding of Intravascular Stents with Genetically Engineered Endothelial Cells" by Dichek et al., in Circulation, vol. 80, No. 5, Nov. 1989 pp. 1347-1353
  • "Restonosis After Balloon Angioplasty" by Schwartz, et al., in Circulation, vol. 82, No. 6, pp. 2190-2198 Dec. 199
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