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Process for preparing pyrrolidinylacetamide derivatives

Patent 5461157 Issued on October 24, 1995. Estimated Expiration Date: Icon_subject December 15, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Process for the condensation of imides and alcohols or amines Patent #: 5059687
Issued on: 10/22/1991
Inventor: Schroder, et al.

Inventors

Assignee

Application

No. 356503 filed on 12/15/1994

US Classes:

548/550Nitrogen attached directly or indirectly to the five-membered hetero ring by acyclic nonionic bonding

Examiners

Primary: Springer, David B.

Attorney, Agent or Firm

International Class

C07D 201/27

Foreign Application Priority Data

1992-06-19 JP

Abstract

A process for preparing a 2-(1-pyrrolidinyl)acetamide derivative useful as a cerebral function improving agent is disclosed, comprising reacting a halogenoacetamide derivative with substituted or unsubstituted 2-pyrrolidinone, the halogenoacetamide derivative being prepared by reacting an amine and a halogenoacetyl chloride. High yields of the intermediate compound as well as the final product are attained at low cost.

Other References

  • Daskalov, Kh.; Georgiev, A.; Konstantinova, K.; (Bulgaria), Tr. Nauchnoizsled Khim.-Farm Inst., (1985). 15. p. 21-32 (and Abstract translated)
  • Yakugaku Zasshi (Pharmacological Journal), vol. 99(2), pp. 146-254 (1979
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